E
E. Le Roux
Researcher at Paris Diderot University
Publications - 21
Citations - 308
E. Le Roux is an academic researcher from Paris Diderot University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 8, co-authored 11 publications receiving 272 citations. Previous affiliations of E. Le Roux include International Agency for Research on Cancer.
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Journal ArticleDOI
Common dysregulation of Wnt/Frizzled receptor elements in human hepatocellular carcinoma
A. Bengochea,M.M. De Souza,M.M. De Souza,Lydie Lefrançois,Lydie Lefrançois,E. Le Roux,O. Galy,O. Galy,Isabelle Chemin,Isabelle Chemin,M M Kim,Jack R. Wands,C. Trepo,C. Trepo,C. Trepo,Pierre Hainaut,J.Y. Scoazec,Ludmila Vitvitski,Ludmila Vitvitski,Philippe Merle,Philippe Merle,Philippe Merle +21 more
TL;DR: An extensive analysis of the Wnt/Frizzled receptor elements reveals that the dysregulation may be one of the most common and earliest events described thus far during hepatocarcinogenesis.
Journal ArticleDOI
Methodology used in comparative studies assessing programmes of transition from paediatrics to adult care programmes: a systematic review
E. Le Roux,H. Mellerio,Sophie Guilmin-Crepon,S. Gottot,Paul Jacquin,Rym Boulkedid,Corinne Alberti +6 more
TL;DR: Systematic review of comparative studies assessing transition to adult care interventions for young people with chronic conditions identified areas for improvement in terms of randomisation, recruitment and external validity, blinding, measurement validity, standardised assessment and reporting.
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Clinical isolates of Campylobacter mucosalis.
TL;DR: The insertion element IS987 from Mycobacterium bovis BCG is located in a hot spot region for insertion elements in M. tuberculosis complex strains, and its application for strain differentiation by a novel method is proposed.
Journal ArticleDOI
Application of a Novel, Rapid, and Sensitive Oligonucleotide Ligation Assay for Detection of Cancer-Predicting Mutations in the Precore and Basal Core Promoter of Hepatitis B Virus
Maimuna Mendy,Steve Kaye,E. Le Roux,Gregory D. Kirk,A. Jeng-Barry,Samuel J. McConkey,Matthew Cotten,Mark H. Kuniholm,Aleksandra Leligdowicz,Pierre Hainaut,Sarah Rowland-Jones,Hilton Whittle +11 more
TL;DR: OLA is a simple, economical, and reliable assay for detection of pre-C and BCP mutations in HBV carriers and can lead to improvement in diagnosis and clinical care in regions where HBV is endemic.
Journal ArticleDOI
Somatic mutations in human cancer: applications in molecular epidemiology.
TL;DR: TP53 mutations have multiple applications as markers of mutagenic exposures, or as intermediate end-points in assessment of cancer occurrence and progression, recently detected in surrogate sources of genetic material such as free circulating DNA isolated from plasma.