E
Ed X. Wu
Researcher at University of Hong Kong
Publications - 363
Citations - 10391
Ed X. Wu is an academic researcher from University of Hong Kong. The author has contributed to research in topics: Diffusion MRI & Magnetic resonance imaging. The author has an hindex of 47, co-authored 343 publications receiving 9190 citations. Previous affiliations of Ed X. Wu include Southern Medical University & Li Ka Shing Faculty of Medicine, University of Hong Kong.
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Journal ArticleDOI
LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis
Sha Mi,Bing Hu,Bing Hu,Kyungmin Hahm,Yi Luo,Edward S. Hui,Qiuju Yuan,Wai-Man Wong,Li Wang,Huanxing Su,Tak-Ho Chu,Jiasong Guo,Wenming Zhang,Kwok-Fai So,Pepinsky R Blake,Zhaohui Shao,Christilyn Graff,Ellen Garber,Vincent Jung,Ed X. Wu,Wutian Wu,Wutian Wu +21 more
TL;DR: Antagonism of LINGO-1 or its pathway is a promising approach for the treatment of demyelinating diseases of the CNS by reflected biologically by improved axonal integrity, as confirmed by magnetic resonance diffusion tensor imaging, and by newly formed myelin sheaths, as determined by electron microscopy.
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SOAP3-dp: Fast, Accurate and Sensitive GPU-based Short Read Aligner
Ruibang Luo,Thomas K. F. Wong,Jianqiao Zhu,Jianqiao Zhu,Chi-Man Liu,Xiaoqian Zhu,Ed X. Wu,Lap-Kei Lee,Haoxiang Lin,Wenjuan Zhu,David W. Cheung,Hing-Fung Ting,Siu-Ming Yiu,Shaoliang Peng,Chang Yu,Yingrui Li,Ruiqiang Li,Tak-Wah Lam +17 more
TL;DR: Compared with widely adopted aligners including BWA, Bowtie2, SeqAlto, CUSHAW2, GEM and GPU-based aligners, SOAP3-dp was found to be two to tens of times faster, while maintaining the highest sensitivity and lowest false discovery rate (FDR) on Illumina reads with different lengths.
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Multifunctional yolk-shell nanoparticles: a potential MRI contrast and anticancer agent.
Jinhao Gao,Gaolin Liang,Jerry S. Cheung,Yue Pan,Yi Kuang,Fan Zhao,Bei Zhang,Xixiang Zhang,Ed X. Wu,Bing Xu +9 more
TL;DR: It is indicated that these unique yolk-shell nanoparticles may ultimately lead to new designs of multifunctional nanostructures for nanomedicine, and may serve both as an MRI contrast agent and as a potent anticancer drug.
Journal ArticleDOI
MR diffusion kurtosis imaging for neural tissue characterization
Ed X. Wu,Matthew M. Cheung +1 more
TL;DR: It is demonstrated that DKI offers a more comprehensive approach than DTI in describing the complex water diffusion process in vivo by estimating both diffusivity and kurtosis, which may provide improved sensitivity and specificity in MR diffusion characterization of neural tissues.
Journal ArticleDOI
SOAP3: ultra-fast GPU-based parallel alignment tool for short reads.
Chi-Man Liu,Thomas K. F. Wong,Ed X. Wu,Ruibang Luo,Siu-Ming Yiu,Yingrui Li,Bingqiang Wang,Chang Yu,Xiaowen Chu,Kaiyong Zhao,Ruiqiang Li,Tak-Wah Lam +11 more
TL;DR: SOAP3 is the first short read alignment tool that leverages the multi-processors in a graphic processing unit (GPU) to achieve a drastic improvement in speed and aligns slightly more reads than BWA and Bowtie.