Edward M. Tilmont

TL;DR: A separation between health effects, morbidity and mortality, and similar to what has been shown in rodents, study design, husbandry and diet composition may strongly affect the life-prolonging effect of CR in a long-lived nonhuman primate is suggested.

TL;DR: It is reported that a low-calorie diet can lessen the severity of neurochemical deficits and motor dysfunction in a primate model of Parkinson's disease and levels of glial cell line-derived neurotrophic factor were increased significantly in the caudate nucleus of CR monkeys, suggesting a role for glialcell line- derived neurotrophic factors in the anti-Parkinson's disease effect of the low-Calorie diet.

TL;DR: Reductions in body temperature and energy expenditure are consistent with findings in rodent studies in which aging rate was retarded by CR, strengthening the possibility that CR may exert beneficial effects in primates analogous to those observed in rodents.

TL;DR: Chronic administration of resveratrol exerts beneficial metabolic and inflammatory adaptations in visceral WAT from diet-induced obese monkeys, which is associated with a chronic, low-grade, systemic inflammation.

TL;DR: In rhesus monkeys, a 2 year diet high in fat and sucrose increases not only body weight and cholesterol, but also induces prominent central arterial wall stiffening and increases PWV and inflammation, and dietary resveratrol prevented the HFS-inducedarterial wall inflammation and the accompanying increase in PWV.