E
Eiichi Tanaka
Researcher at Stanford University
Publications - 140
Citations - 2347
Eiichi Tanaka is an academic researcher from Stanford University. The author has contributed to research in topics: Rheumatoid arthritis & Rheumatology. The author has an hindex of 24, co-authored 116 publications receiving 1992 citations.
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Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses.
Wako Urano,Atsuo Taniguchi,Hisashi Yamanaka,Eiichi Tanaka,Hiroshi Nakajima,Yuko Matsuda,Hideto Akama,Yutaka Kitamura,Naoyuki Kamatani +8 more
TL;DR: Both single locus and haplotype analyses suggest that polymorphisms within the MTHFR gene are associated with both the efficacy and toxicity of MTX in rheumatoid arthritis patients.
Journal ArticleDOI
Validation of a Japanese version of the Stanford Health Assessment Questionnaire in 3,763 patients with rheumatoid arthritis
Yuko Matsuda,Gurkirpal Singh,Hisashi Yamanaka,Eiichi Tanaka,Wako Urano,Atsuo Taniguchi,Terunobu Saito,Masako Hara,Taisuke Tomatsu,Naoyuki Kamatani +9 more
TL;DR: The final version of the J-HAQ is a valid and reliable instrument for measuring functional status in Japanese-speaking RA patients and shows excellent internal reliability.
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Comparison of adding tocilizumab to methotrexate with switching to tocilizumab in patients with rheumatoid arthritis with inadequate response to methotrexate: 52-week results from a prospective, randomised, controlled study (SURPRISE study).
Yuko Kaneko,Tatsuya Atsumi,Yoshiya Tanaka,Masayuki Inoo,Hitomi Kobayashi-Haraoka,Koichi Amano,Masayuki Miyata,Yohko Murakawa,Hidekata Yasuoka,Shintaro Hirata,Hayato Nagasawa,Eiichi Tanaka,Nobuyuki Miyasaka,Hisashi Yamanaka,Kazuhiko Yamamoto,Tsutomu Takeuchi +15 more
TL;DR: In RA patients with inadequate response to methotrexate, tocilizumab added to metotrexate more rapidly suppressed inflammation than tocilIZumab switched from methot Rexate, leading to superior clinical efficacy and prevention of joint destruction.
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Validation of the associations between single nucleotide polymorphisms or haplotypes and responses to disease-modifying antirheumatic drugs in patients with rheumatoid arthritis: a proposal for prospective pharmacogenomic study in clinical practice.
Atsuo Taniguchi,Wako Urano,Eiichi Tanaka,Shiori Furihata,Shigeo Kamitsuji,Eisuke Inoue,Mariko Yamanaka,Hisashi Yamanaka,Naoyuki Kamatani +8 more
TL;DR: Three retrospective studies on the associations between genomic variations and adverse events or efficacy of two different disease-modifying antirheumatic drugs were replicated and the usefulness of the tests is worth being tested in clinical practice.
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Increased risk of tuberculosis in patients with rheumatoid arthritis in Japan
Toru Yamada,Ayako Nakajima,Eisuke Inoue,Eiichi Tanaka,Masako Hara,Taisuke Tomatsu,Naoyuki Kamatani,Hisashi Yamanaka +7 more
TL;DR: There was an increased risk of tuberculosis infection in Japanese patients with rheumatoid arthritis, especially in male patients before the introduction of anti-tumour necrosis factor treatment, and these data should form the basis for the risk management ofAnti-cytokine treatment in Japan.