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Elena Ciaglia
Researcher at University of Salerno
Publications - 70
Citations - 2216
Elena Ciaglia is an academic researcher from University of Salerno. The author has contributed to research in topics: Medicine & Immune system. The author has an hindex of 19, co-authored 56 publications receiving 1653 citations. Previous affiliations of Elena Ciaglia include University of Naples Federico II.
Papers
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Journal ArticleDOI
Pharmacological Actions of Statins: A Critical Appraisal in the Management of Cancer
Patrizia Gazzerro,Maria Proto,Giuseppina Gangemi,Anna Maria Malfitano,Elena Ciaglia,Simona Pisanti,Antonietta Santoro,Chiara Laezza,Maurizio Bifulco +8 more
TL;DR: The pharmacology of the statins is reviewed, providing a comprehensive update of the current knowledge of their effects on tissues, biological processes, and pathological conditions, and the disappointing evidence on the possible future use of statin-based drugs in cancer therapy is dissected.
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Cannabidiol: State of the art and new challenges for therapeutic applications
Simona Pisanti,Anna Maria Malfitano,Elena Ciaglia,Anna Lamberti,Roberta Ranieri,Gaia Cuomo,Mario Abate,Giorgio Faggiana,Maria Proto,Donatella Fiore,Chiara Laezza,Maurizio Bifulco +11 more
TL;DR: This review highlights the pharmacological activities of CBD, its cannabinoid receptor-dependent and -independent action, its biological effects focusing on immunomodulation, angiogenetic properties, and modulation of neuronal and cardiovascular function, and the therapeutic potential of cannabidiol.
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COVID-19 Infection and Circulating ACE2 Levels: Protective Role in Women and Children
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Enrichment of CD56 dim KIR+CD57+ highly cytotoxic NK cells in tumour-infiltrated lymph nodes of melanoma patients
Talib Hassan Ali,Simona Pisanti,Elena Ciaglia,Roberta Mortarini,Andrea Anichini,Cinzia Garofalo,Rossana Tallerico,Mario Santinami,Elio Gulletta,Caterina Ietto,Mario Galgani,Giuseppe Matarese,Maurizio Bifulco,Soldano Ferrone,Francesco Colucci,Alessandro Moretta,Klas Kärre,Ennio Carbone +17 more
TL;DR: The data suggest that the microenvironment of TILN generates and/or recruits a particularly effective NK cell subset in the metastasis to lymph nodes of patients with metastatic melanoma.
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Novel prospects of statins as therapeutic agents in cancer
TL;DR: The anti-tumor effects of statins are discussed, underpinning the detailed mode of action and looking for their true significance in cancer prevention and treatment, to determine if and in which case statin repositioning could be really justified for neoplastic diseases.