Mario Abate

TL;DR: This review highlights the pharmacological activities of CBD, its cannabinoid receptor-dependent and -independent action, its biological effects focusing on immunomodulation, angiogenetic properties, and modulation of neuronal and cardiovascular function, and the therapeutic potential of cannabidiol.

TL;DR: The creation of national networks that can collect patients’ samples from all regions for HLA typing should be highly encouraged and the two most frequent HLA haplotypes in the Italian population showed respectively a positive and negative correlation with both Covid-19 incidence and mortality.

TL;DR: Results suggest that 9,11-dihydrogracilin A exerts anti-inflammatory effects and its anti-edema activity in vivo strongly supports its potential therapeutic application in inflammatory cutaneous diseases.

TL;DR: A more refined map of the connectivity between signal transduction pathways and metabolic networks in cancer FDPS as a new candidate metabolic oncogene in glioblastoma might suggest to further target MVA pathway as valid therapeutic tool.

TL;DR: This study provides the first evidence of iPA antiglioma effect as glioma is driven by aberrant signaling of growth factor receptors, particularly the EGFR, and iPA, alone or in association with EGFR targeted therapies, might be a promising therapeutic tool to achieve a potent anti‐tumoral effect.