Elena Tenedini

TL;DR: It is shown that muscle pericytes, which are not spontaneously osteochondrogenic as previously claimed, may indeed coincide with an ectopic perivascular subset of committed myogenic cells similar to satellite cells, and the data support the view that different mesoderm derivatives include distinct classes of tissue-specific committed progenitors, possibly of different developmental origin.

TL;DR: This study demonstrates that NGS represents a comprehensive cost-effective approach for IRDs molecular diagnosis, and the identification of the genetic alterations underlying the phenotype enabled the clinicians to achieve a more accurate diagnosis.

TL;DR: It is demonstrated that embryonic and fetal myoblasts represent intrinsically different myogenic lineages and provide important information for the understanding of the molecular mechanisms governing skeletal muscle development.

TL;DR: Data indicate that clinical efficacy and survival improvement may occur across different molecular subsets of patients with MF treated with ruxolitinib.

TL;DR: The data collectively demonstrate that c-myb plays a pivotal role in human primary hematopoietic stem/progenitor cells lineage commitment, by enhancing erythropoiesis at the expense of megakaryocyte diffentiation.