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Elio Cenci
Researcher at University of Perugia
Publications - 112
Citations - 6489
Elio Cenci is an academic researcher from University of Perugia. The author has contributed to research in topics: Candida albicans & Immune system. The author has an hindex of 44, co-authored 111 publications receiving 6223 citations. Previous affiliations of Elio Cenci include Stanford University.
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Journal ArticleDOI
Impaired neutrophil response and CD4+ T helper cell 1 development in interleukin 6-deficient mice infected with Candida albicans.
Luigina Romani,Antonella Mencacci,Elio Cenci,Roberta Spaccapelo,C Toniatti,Paolo Puccetti,Francesco Bistoni,Valeria Poli +7 more
TL;DR: In this paper, the role of interleukin (IL)6 in Candida albicans infection was defined and IL-6 deficient mice were assessed for susceptibility to systemic or gastrointestinal infection, as well as for parameters of elicited T helper cell immunity.
Journal ArticleDOI
Interleukin-4 and interleukin-10 inhibit nitric oxide-dependent macrophage killing of Candida albicans.
Elio Cenci,Luigina Romani,Antonella Mencacci,Roberta Spaccapelo,Enrico Schiaffella,Paolo Puccetti,Francesco Bistoni +6 more
TL;DR: It is demonstrated that NO is involved in macrophage killing of C. albicans and support the notion that regulation of Th1 effector function by IL‐4 and IL‐10 might involve modulation of NO synthesis.
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Evidence for macrophage-mediated protection against lethal Candida albicans infection.
Francesco Bistoni,Anna Vecchiarelli,Elio Cenci,Paolo Puccetti,Pierfrancesco Marconi,Antonio Cassone +5 more
TL;DR: It was found that administration of PCA-2 was accompanied by an increase in the number of peripheral blood polymorphonuclear cells and by the activation in the spleen of cells with highly candidacidal activity in vitro, which conferred considerable protection against subsequent CA-6 challenge.
Journal ArticleDOI
Cytokine- and T Helper-Dependent Lung Mucosal Immunity in Mice with Invasive Pulmonary Aspergillosis
Elio Cenci,Antonella Mencacci,Cristiana Fè d'Ostiani,Giuseppe Del Sero,Paolo Mosci,Claudia Montagnoli,Angela Bacci,Luigina Romani +7 more
TL;DR: Results indicate that, similar to observations in mice with disseminated aspergillosis, innate and Th1-dependent immunity play an essential role in host defense against IPA.
Journal ArticleDOI
Th1 and Th2 cytokines in mice with invasive aspergillosis.
Elio Cenci,Stefano Perito,Karl-Heinz Enssle,Paolo Mosci,Jean-Paul Latgé,Luigina Romani,Francesco Bistoni +6 more
TL;DR: Findings indicate that in murine invasive aspergillosis, production of IL-4 by CD4+ T cells may be one major factor discriminating susceptibility and resistance to infection.