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Emerita Caputo

Researcher at Johns Hopkins University

Publications -  6
Citations -  4196

Emerita Caputo is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Gene & Retrotransposon. The author has an hindex of 5, co-authored 6 publications receiving 3873 citations. Previous affiliations of Emerita Caputo include Johns Hopkins University School of Medicine.

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Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications.

TL;DR: A set of yeast strains based on Saccharomyces cerevisiae S288C in which commonly used selectable marker genes are deleted by design based on the yeast genome sequence has been constructed and analysed and will reduce plasmid integration events which can interfere with a wide variety of molecular genetic applications.
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Human L1 Retrotransposition Is Associated with Genetic Instability In Vivo

TL;DR: A genetic system to recover many new L1 insertions in somatic cells was developed that faithfully mimic many aspects of L1s that accumulated since the primate radiation, and short identical sequences were shared between the donor and the target site's 3' end, suggesting a mechanistic model that helps explain the structure of L 1 insertions.
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A Genetic Screen for Ribosomal DNA Silencing Defects Identifies Multiple DNA Replication and Chromatin-Modulating Factors

TL;DR: Several lrs mutants, including those in the cdc17 and rfc1 genes, caused lengthened telomeres, consistent with the hypothesis that telomere length modulates rDNA silencing.
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Sequence analysis of closely related retrotransposon families from fission yeast

TL;DR: In this article, the nucleotide (nt) sequence of a Tf2 element, the only retrotransposon family known from the commonly used laboratory strains, 972 and 975, and their derivatives, has been isolated from the fission yeast, Schizosaccharomyces pombe.
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Retrotransposon overdose and genome integrity

TL;DR: This work describes the identification of mutants in the DNA replication pathway that enhance this RO-specific DNA damage supersensitivity by promoting ectopic recombination between Ty1 elements and confirms the central role of DNA replication accuracy in the stabilization of repetitive DNA.