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Emma J. Birks
Researcher at Imperial College London
Publications - 80
Citations - 4297
Emma J. Birks is an academic researcher from Imperial College London. The author has contributed to research in topics: Heart failure & Ventricular assist device. The author has an hindex of 34, co-authored 80 publications receiving 4065 citations. Previous affiliations of Emma J. Birks include National Health Service & Harefield Hospital.
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Journal ArticleDOI
Left ventricular assist device and drug therapy for the reversal of heart failure.
Emma J. Birks,Patrick Tansley,J Hardy,Robert S. George,Christopher Bowles,Margaret Burke,Nicholas R. Banner,Asghar Khaghani,Magdi H. Yacoub +8 more
TL;DR: It is found that sustained reversal of severe heart failure secondary to nonischemic cardiomyopathy could be achieved in selected patients with the use of a left ventricular assist device and a specific pharmacologic regimen.
Journal ArticleDOI
Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease
Angharad M. Roberts,Angharad M. Roberts,James S. Ware,Daniel S. Herman,Daniel S. Herman,Daniel S. Herman,Sebastian Schafer,John Baksi,Alexander G. Bick,Alexander G. Bick,Rachel Buchan,Roddy Walsh,Shibu John,S Wilkinson,Francesco Mazzarotto,Francesco Mazzarotto,Leanne E. Felkin,Leanne E. Felkin,Sungsam Gong,Jacqueline A. L. MacArthur,Fiona Cunningham,Jason Flannick,Jason Flannick,Stacey Gabriel,David Altshuler,David Altshuler,Peter S. Macdonald,Peter S. Macdonald,Peter S. Macdonald,Matthias Heinig,Anne Keogh,Anne Keogh,Anne Keogh,Christopher S. Hayward,Christopher S. Hayward,Christopher S. Hayward,Nicholas R. Banner,Nicholas R. Banner,Dudley J. Pennell,Dudley J. Pennell,Declan P. O'Regan,Tan Ru San,Antonio de Marvao,Timothy J W Dawes,Ankur Gulati,Emma J. Birks,Emma J. Birks,Magdi H. Yacoub,Michael H. Radke,Michael Gotthardt,James G. Wilson,Christopher J. O'Donnell,Sanjay K Prasad,Paul J.R. Barton,Paul J.R. Barton,Diane Fatkin,Diane Fatkin,Diane Fatkin,Norbert Hubner,Norbert Hubner,Jonathan G. Seidman,Christine E. Seidman,Stuart A. Cook +62 more
TL;DR: It is shown that TTNtv is the most common genetic cause of DCM in ambulant patients in the community, identify clinically important manifestations ofTTNtv-positive DCM, and define the penetrance and outcomes of TTNTV in the general population.
Journal ArticleDOI
The aortic outflow and root: a tale of dynamism and crosstalk.
TL;DR: The interaction and the specific operations are presented with evidence supporting the notion that the dynamic behavior of the root does influence the pattern of instantaneous movements of the aortic cusps after different types of operations.
Journal ArticleDOI
Clinical Recovery From End-Stage Heart Failure Using Left-Ventricular Assist Device and Pharmacological Therapy Correlates With Increased Sarcoplasmic Reticulum Calcium Content but Not With Regression of Cellular Hypertrophy
Cesare M. Terracciano,John Hardy,Emma J. Birks,Asghar Khaghani,Nicholas R. Banner,Magdi H. Yacoub +5 more
TL;DR: These results show that specific changes in excitation-contraction coupling, and not regression of cellular hypertrophy, are specifically associated with clinical recovery after LVAD and further identify sarcoplasmic reticulum Ca2+ handling as a key functional determinant in patients with heart failure.
Journal ArticleDOI
Early and long-term results of a valve-sparing operation for Marfan syndrome.
TL;DR: Valve-sparing operations are feasible in most patients with Marfan syndrome; they are applicable to patients with both dissection and chronic aneurysm and prophylactic operation is warranted in some cases.