E
Eran Meshorer
Researcher at Hebrew University of Jerusalem
Publications - 135
Citations - 9515
Eran Meshorer is an academic researcher from Hebrew University of Jerusalem. The author has contributed to research in topics: Chromatin & Embryonic stem cell. The author has an hindex of 40, co-authored 127 publications receiving 8438 citations. Previous affiliations of Eran Meshorer include National Institutes of Health.
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Journal ArticleDOI
Hyperdynamic Plasticity of Chromatin Proteins in Pluripotent Embryonic Stem Cells
Eran Meshorer,Dhananjay Yellajoshula,Eric M. George,Peter J. Scambler,David T. Brown,Tom Misteli +5 more
TL;DR: It is suggested that hyperdynamic binding of structural chromatin proteins is a functionally important hallmark of pluripotent ES cells that contributes to the maintenance of plasticity in undifferentiated ES cells and to establishing higher-order chromatin structure.
Journal ArticleDOI
Chromatin in pluripotent embryonic stem cells and differentiation
Eran Meshorer,Tom Misteli +1 more
TL;DR: This work discusses how unique properties of chromatin in ES cells contribute to the maintenance of pluripotency and the determination of differentiation properties.
Journal ArticleDOI
Global Transcription in Pluripotent Embryonic Stem Cells
Sol Efroni,Radharani Duttagupta,Jill Cheng,Hesam Dehghani,Daniel J. Hoeppner,Chandravanu Dash,David P. Bazett-Jones,Stuart F.J. Le Grice,Ronald D.G. McKay,Kenneth H. Buetow,Thomas R. Gingeras,Tom Misteli,Eran Meshorer +12 more
TL;DR: It is proposed that global transcription is a hallmark of pluripotent ESCs, contributing to their plasticity, and that lineage specification is driven by reduction of the transcribed portion of the genome.
Journal ArticleDOI
Chromatin organization marks exon-intron structure.
TL;DR: The findings indicate that previously described enrichment of H3K36me3 modifications in exons reflects a more fundamental phenomenon, namely increased nucleosome occupancy along exons, implying that exon selection may be modulated by chromatin structure.
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Open chromatin in pluripotency and reprogramming
TL;DR: Two principles are emerging: specific factors maintain a globally open chromatin state that is accessible for transcriptional activation; and other chromatin regulators contribute locally to the silencing of lineage-specific genes until differentiation is triggered.