E
Eric Mickelson
Researcher at Fred Hutchinson Cancer Research Center
Publications - 106
Citations - 7256
Eric Mickelson is an academic researcher from Fred Hutchinson Cancer Research Center. The author has contributed to research in topics: Human leukocyte antigen & Transplantation. The author has an hindex of 40, co-authored 106 publications receiving 7165 citations. Previous affiliations of Eric Mickelson include University of Washington & Hebrew University of Jerusalem.
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Journal ArticleDOI
Marrow transplantation from related donors other than HLA-identical siblings.
Patrick G. Beatty,Reginald A. Clift,Eric Mickelson,Brenda Nisperos,Nancy Flournoy,Paul J. Martin,Jean E. Sanders,P Stewart,Buckner Cd,Rainer Storb +9 more
TL;DR: In a study of the acceptable limits of HLA incompatibility, 105 consecutive patients with hematologic cancers who received marrow grafts from haploidentical donors were compared with 728 similar patients concurrently receiving grafting from HLA genotypically identical siblings.
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Effect of HLA compatibility on engraftment of bone marrow transplants in patients with leukemia or lymphoma.
Claudio Anasetti,D. Amos,Patrick G. Beatty,Frederick R. Appelbaum,William I. Bensinger,Buckner Cd,Reginald A. Clift,Kristine Doney,Paul J. Martin,Eric Mickelson +9 more
TL;DR: It is concluded that donor HLA incompatibility and prior alloimmunization are significant risk factors for graft failure, and that a more effective immunosuppressive regimen than those currently used is needed for consistent achievement of sustained engraftment of marrow transplanted from donors who are not HLA-identical siblings.
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Optimizing Outcome After Unrelated Marrow Transplantation by Comprehensive Matching of HLA Class I and II Alleles in the Donor and Recipient
Effie W. Petersdorf,Ted Gooley,Claudio Anasetti,Paul J. Martin,Anajane G. Smith,Eric Mickelson,Ann E. Woolfrey,John A. Hansen +7 more
TL;DR: It is concluded that matching HLA class I and class II alleles of the donor and recipient can improve outcome after unrelated marrow transplantation.
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Killer Ig-Like Receptor Haplotype Analysis by Gene Content: Evidence for Genomic Diversity with a Minimum of Six Basic Framework Haplotypes, Each with Multiple Subsets
Katharine C. Hsu,Xiao-Rong Liu,Annamalai Selvakumar,Eric Mickelson,Richard J. O’Reilly,Richard J. O’Reilly,Bo Dupont,Bo Dupont +7 more
TL;DR: The studies support a model for KIR haplotype diversity based on six basic gene compositions, and suggest that the centromeric half of the KIR genomic region is comprised of three major combinations, while the telomeric half can assume a short form with either 2DS4 or KIR1D or a long form with multiple combinations of several stimulatory KIR genes.
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Major-Histocompatibility-Complex Class I Alleles and Antigens in Hematopoietic-Cell Transplantation
Effie W. Petersdorf,John A. Hansen,Paul J. Martin,Ann E. Woolfrey,Mari Malkki,Ted Gooley,Barry E. Storer,Eric Mickelson,Anajane G. Smith,Claudio Anasetti +9 more
TL;DR: HLA class I antigen mismatches that are serologically detectable confer an enhanced risk of graft failure after hematopoietic-cell transplantation.