Eric Viara

TL;DR: This work applied HiC-Pro to different Hi-C datasets, demonstrating its ability to easily process large data in a reasonable time and its fast implementation of the iterative correction method.

TL;DR: The Atlas of Cancer Signalling Network (ACSN) is presented, an interactive and comprehensive map of molecular mechanisms implicated in cancer, including DNA repair, cell survival, apoptosis, cell cycle, EMT and cell motility, which may help interpret their biological significance and formulate mechanistic hypotheses.

TL;DR: A graphical user interface for visualization and first level analysis of molecular profiles is developed and currently in use at the Institut Curie for cancer research projects involving CGH arrays, transcriptome arrays, SNP (single nucleotide polymorphism) arrays, loss of heterozygosity results (LOH), and Chromatin ImmunoPrecipitation arrays (ChIP chips).

TL;DR: BiNoM is a new bioinformatics software that significantly facilitates the usage and the analysis of biological networks in standard systems biology formats and adds a rich set of operations to Cytoscape such as path and cycle analysis, clustering sub-networks, decomposition of network into modules, clipboard operations and others.

TL;DR: An algorithm for modeling biological networks in a discrete framework with continuous time based on continuous time Markov process applied on a Boolean state space, which allows to describe kinetic phenomena which were difficult to handle in the original models.