V
Virginie Raynal
Researcher at PSL Research University
Publications - 56
Citations - 4868
Virginie Raynal is an academic researcher from PSL Research University. The author has contributed to research in topics: Gene & Rh blood group system. The author has an hindex of 33, co-authored 50 publications receiving 4293 citations. Previous affiliations of Virginie Raynal include Curie Institute & French Institute of Health and Medical Research.
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Journal ArticleDOI
Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma
Isabelle Janoueix-Lerosey,Delphine Lequin,Delphine Lequin,Laurence Brugières,Agnès Ribeiro,Loïc de Pontual,Valérie Combaret,Virginie Raynal,Virginie Raynal,Alain Puisieux,Alain Puisieux,Gudrun Schleiermacher,Gudrun Schleiermacher,Gaëlle Pierron,Dominique Valteau-Couanet,Thierry Frebourg,Jean Michon,Stanislas Lyonnet,Jeanne Amiel,Olivier Delattre,Olivier Delattre +20 more
TL;DR: In this paper, the authors conducted genome-wide comparative genomic hybridization analysis on a large series of neuroblastomas and found that the copy number increase at the locus encoding the anaplastic lymphoma kinase tyrosine kinase receptor was observed recurrently.
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Genetic basis of the RhD-positive and RhD-negative blood group polymorphism as determined by Southern analysis
TL;DR: It is shown that the Rh locus carried by the genome of RhD-positive individuals is composed of two different but strongly related genes of identical general organization whether they expressed the C or c and E or e antigens, and, surprisingly, even when they do not express these epitopes.
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The human Rhesus-associated RhAG protein and a kidney homologue promote ammonium transport in yeast.
Anne-Marie Marini,Giorgio Matassi,Giorgio Matassi,Virginie Raynal,Bruno André,Jean-Pierre Cartron,Baya Cherif-Zahar +6 more
TL;DR: It is shown here that RhAG and also RhGK, a new human homologue expressed in kidney cells only, function as ammonium transport proteins when expressed in yeast, and specifically complement the growth defect of a yeast mutant deficient in ammonium uptake.
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Heterogeneity of neuroblastoma cell identity defined by transcriptional circuitries
Valentina Boeva,Valentina Boeva,Caroline Louis-Brennetot,Agathe Peltier,Simon Durand,Cécile Pierre-Eugène,Virginie Raynal,Virginie Raynal,Heather C. Etchevers,Sophie Thomas,Alban Lermine,Estelle Daudigeos-Dubus,Birgit Geoerger,Martin F. Orth,Thomas G. P. Grunewald,Elise Diaz,Elise Diaz,Bertrand Ducos,Bertrand Ducos,Bertrand Ducos,Didier Surdez,Angel M. Carcaboso,Irina V. Medvedeva,Thomas Deller,Valérie Combaret,Eve Lapouble,Gaëlle Pierron,Sandrine Grossetête-Lalami,Sylvain Baulande,Gudrun Schleiermacher,Emmanuel Barillot,Hermann Rohrer,Olivier Delattre,Olivier Delattre,Isabelle Janoueix-Lerosey,Isabelle Janoueix-Lerosey +35 more
TL;DR: This work discovered three types of identity in neuroblastoma cell lines: a sympathetic noradrenergic identity, defined by a CRC module including the PHOX2B, HAND2 and GATA3 transcription factors (TFs); an NCC-like identity, driven by aRC module containing AP-1 TFs; and a mixed type, further deconvoluted at the single-cell level.
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Molecular cloning and primary structure of the human blood group RhD polypeptide.
TL;DR: The sequence homology between the Cc/Ee and D proteins supports the concept that the genes encoding these polypeptides have evolved by duplication of a common ancestor gene.