E
Erica Lieberman
Researcher at Stanford University
Publications - 6
Citations - 207
Erica Lieberman is an academic researcher from Stanford University. The author has contributed to research in topics: Gene & Cas9. The author has an hindex of 2, co-authored 4 publications receiving 70 citations.
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Journal ArticleDOI
A fully decompressed synthetic bacteriophage øX174 genome assembled and archived in yeast.
TL;DR: It is expected that yeast can serve as a genomic 'drydock' within which to maintain and manipulate clonal lineages of other obligate lytic phage as well as fully separates all primary phage protein coding sequences along with cognate translation control elements.
Journal ArticleDOI
Phages and their satellites encode hotspots of antiviral systems
François Rousset,Florence Depardieu,Solange Ana Belén Miele,J E Dowding,Anne-Laure Laval,Erica Lieberman,Daniel Garry,Eduardo P. C. Rocha,Aude Bernheim,David Bikard +9 more
TL;DR: In this article , the authors show that E. coli P2-like phages and their parasitic P4-like satellites carry hotspots of genetic variation containing reservoirs of anti-phage systems.
Journal ArticleDOI
Phage–host coevolution in natural populations
Damien Piel,Maxime Bruto,Yannick Labreuche,François Blanquart,David Goudenège,Rubén Barcia-Cruz,Sabine Chenivesse,Sophie Le Panse,Adèle James,Javier Dubert,Bruno Petton,Erica Lieberman,K. Mathias Wegner,Fatima A. Hussain,Kathryn M. Kauffman,Martin F. Polz,David Bikard,Sylvain Gandon,Eduardo P. C. Rocha,Frédérique Le Roux +19 more
TL;DR: In this article , the evolution of bacterial defences and phage counter-defences is underpinned by frequent genetic exchanges with, and between, mobile genetic elements, and multiple defences are active within a single genome.
Posted ContentDOI
Genetic determinism of phage-bacteria coevolution in natural populations
Damien Piel,Damien Piel,Maxime Bruto,Yannick Labreuche,Yannick Labreuche,François Blanquart,Sabine Chenivesse,Sophie Lepanse,Adèle James,Rubén Barcia-Cruz,Rubén Barcia-Cruz,Javier Dubert,Javier Dubert,Bruno Petton,Erica Lieberman,K. Mathias Wegner,Fatima A. Hussain,Kathryn M. Kauffman,Martin F. Polz,Martin F. Polz,David Bikard,Sylvain Gandon,Frédérique Le Roux,Frédérique Le Roux +23 more
TL;DR: In this paper, the authors explored the genetic structure of phage-vibrio coevolution and proposed a pan-escape system that can be shared among phages by homologous recombination within a population that infects a bacterial host.
Posted ContentDOI
CRISPR/Cas9-Assisted Transformation-Efficient Reaction (CRATER), a novel method for selective transformation
Lynn J. Rothschild,Daniel T. Greenberg,Jack R. Takahashi,Kirsten A. Thompson,Akshay J. Maheshwari,Ryan Kent,Griffin McCutcheon,Joseph D. Shih,Charles Calvet,Tyler D. Devlin,Tina Ju,Daniel Kunin,Erica Lieberman,Thai Nguyen,Forrest Tran,Daniel Z. Xiang,Kosuke Fujishima +16 more
TL;DR: Using fluorescent and chromogenic proteins as reporters, it is demonstrated that CRISPR/Cas9 cleavage excludes unwanted ligation byproducts and increases transformation efficiency of desired inserts from 20% up to 97% ± 3%.