E
Erica Spackman
Researcher at United States Department of Agriculture
Publications - 158
Citations - 8651
Erica Spackman is an academic researcher from United States Department of Agriculture. The author has contributed to research in topics: Influenza A virus subtype H5N1 & Virus. The author has an hindex of 45, co-authored 154 publications receiving 7877 citations. Previous affiliations of Erica Spackman include University of Georgia & University of Minnesota.
Papers
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Journal ArticleDOI
Molecular characterization of avian astroviruses
TL;DR: The results of this study indicate that there are most likely multiple serotypes of each avian astrovirus circulating in commercial poultry.
Journal ArticleDOI
NP, PB1, and PB2 Viral Genes Contribute to Altered Replication of H5N1 Avian Influenza Viruses in Chickens
Jamie L. Wasilenko,Chang-Won Lee,Luciana Sarmento,Erica Spackman,Darrell R. Kapczynski,David L. Suarez,Mary J. Pantin-Jackwood +6 more
TL;DR: While the pathogenesis of AIVs in chickens is clearly dependent on the interaction of multiple gene products, it is shown that single-gene reassortment events are sufficient to alter the virulence of Aivs in poultry.
Journal ArticleDOI
Antibody Titer Has Positive Predictive Value for Vaccine Protection against Challenge with Natural Antigenic-Drift Variants of H5N1 High-Pathogenicity Avian Influenza Viruses from Indonesia
David E. Swayne,David L. Suarez,Erica Spackman,Samadhan Jadhao,Gwenaelle Dauphin,Mia Kim-Torchetti,James McGrane,John Weaver,Peter Daniels,Frank Y. K. Wong,Paul Selleck,Agus Wiyono,Risa Indriani,Yuni Yupiana,Elly Sawitri Siregar,Teguh Y. Prajitno,Derek J. Smith,Ron A. M. Fouchier +17 more
TL;DR: Investigation of Indonesian licensed vaccines, specific vaccine seed strains, and emerging variant field viruses indicate that antigenic variants did emerge in Indonesia following widespread H5 avian influenza vaccine usage, and efficacious inactivated vaccines can be developed using antigenic variant wild-type viruses or rg-generated LPAI virus seed strains containing the hemagglutinin and neuraminidase genes of wild- type viruses.
Book ChapterDOI
A brief introduction to the avian influenza virus.
TL;DR: Type A influenza strains are classified by the serological subtypes of the primary viral surface proteins, the hemagglutinin (HA) and neuraminidase (NA), which seem to be able to assort into any combination, and many of the 144 possible combinations have been found in natural reservoir species, although some combinations are more common than others.
Journal ArticleDOI
Characterization of the 2012 Highly Pathogenic Avian Influenza H7N3 virus isolated from poultry in an outbreak in Mexico: Pathobiology and Vaccine Protection
Darrell R. Kapczynski,Mary J. Pantin-Jackwood,Sofia G. Guzman,Yadira Ricardez,Erica Spackman,Kateri Bertran,David L. Suarez,David E. Swayne +7 more
TL;DR: The authors in this paper characterized the Mexican 2012 H7N3 HPAI virus (A/chicken/Jalisco/CPA1/2012) and determined the protection against the virus conferred by different H7 inactivated vaccines in chickens.