E
Erik Ilsø Christensen
Researcher at Aarhus University
Publications - 202
Citations - 16762
Erik Ilsø Christensen is an academic researcher from Aarhus University. The author has contributed to research in topics: Cubilin & Kidney. The author has an hindex of 66, co-authored 200 publications receiving 15387 citations. Previous affiliations of Erik Ilsø Christensen include French Institute of Health and Medical Research & Aarhus University Hospital.
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Journal ArticleDOI
Vasopressin increases water permeability of kidney collecting duct by inducing translocation of aquaporin-CD water channels to plasma membrane
Søren Nielsen,Chung Lin Chou,David Marples,Erik Ilsø Christensen,Bellamkonda K. Kishore,Mark A. Knepper +5 more
TL;DR: It is concluded that vasopressin increases the water permeability of collecting duct cells by inducing a reversible translocation of AQP-CD water channels from IVs to the APM.
Journal ArticleDOI
Megalin and cubilin: multifunctional endocytic receptors
TL;DR: The ability to take up substances from the surrounding environment not only provides cells with vital nutrients, but also enables the selective transport of substances from one compartment to another.
Journal ArticleDOI
Distribution of the aquaporin CHIP in secretory and resorptive epithelia and capillary endothelia
TL;DR: The aquaporin CHIP (channel-forming integral membrane protein of 28 kDa), a molecular water channel, is abundant in erythrocytes and water-permeable segments of the nephron as mentioned in this paper.
Journal ArticleDOI
The sortilin cytoplasmic tail conveys Golgi–endosome transport and binds the VHS domain of the GGA2 sorting protein
Morten Nielsen,Peder Madsen,Erik Ilsø Christensen,Anders Nykjaer,Jørgen Gliemann,Dagmar Kasper,Regina Pohlmann,Claus Munck Petersen +7 more
TL;DR: Evidence is provided suggesting that sortilin is the first example of a mammalian receptor targeted by the recently described GGA family of cytosolic sorting proteins, which condition the Vps10p‐mediated sorting of yeast carboxypeptidase Y.
Journal ArticleDOI
Megalin Knockout Mice as an Animal Model of Low Molecular Weight Proteinuria
Jörg-Robert Leheste,Boris Rolinski,Henrik Vorum,Jan Hilpert,Anders Nykjaer,Christian Jacobsen,Pierre Aucouturier,Jan Øivind Moskaug,Albrecht Otto,Erik Ilsø Christensen,Thomas E. Willnow +10 more
TL;DR: It is demonstrated that megalin-deficient mice exhibit a tubular resorption deficiency and excrete low molecular weight plasma proteins in the urine (low molecular weight proteinuria) and patients with low molecularWeight proteinuria are shown to excrete vitamin/carrier complexes.