M
Meng C. Wang
Researcher at Baylor College of Medicine
Publications - 88
Citations - 4877
Meng C. Wang is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Longevity & Caenorhabditis elegans. The author has an hindex of 27, co-authored 73 publications receiving 3784 citations. Previous affiliations of Meng C. Wang include Howard Hughes Medical Institute & Harvard University.
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JNK Extends Life Span and Limits Growth by Antagonizing Cellular and Organism-Wide Responses to Insulin Signaling
TL;DR: It is shown that JNK requires Foxo to extend life span in Drosophila, and the convergence of JNK signaling and IIS on Foxo provides a model to explain the effects of stress and nutrition on longevity.
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JNK Signaling Confers Tolerance to Oxidative Stress and Extends Lifespan in Drosophila
TL;DR: The Jun N-terminal kinase (JNK) signaling pathway is introduced as a genetic determinant of aging in Drosophila melanogaster and it is shown that flies with mutations that augment JNK signaling accumulate less oxidative damage and live dramatically longer than wild-type flies.
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Fat metabolism links germline stem cells and longevity in C. elegans.
TL;DR: It is found that germline stem cells (GSCs) actively modulate lipid hydrolysis in Caenorhabditis elegans, which in turn regulates longevity, suggesting a link between C. elegans fat metabolism and longevity.
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Live-cell imaging of alkyne-tagged small biomolecules by stimulated Raman scattering
TL;DR: In this paper, the authors used stimulated Raman-scattering imaging of alkyne tags as a general strategy for studying a broad spectrum of small biomolecules in live cells and animals.
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Microbial Genetic Composition Tunes Host Longevity.
Bing Han,Priya Sivaramakrishnan,Chih-Chun J Lin,Isaiah A.A. Neve,Jingquan He,Li Wei Rachel Tay,Jessica N. Sowa,Antons Sizovs,Guangwei Du,Jin Wang,Christophe Herman,Meng C. Wang +11 more
TL;DR: Together, the results identified molecular targets for developing pro-longevity microbes and a bacterial metabolite acting on host mitochondria to promote longevity.