E
Ernest B. Cady
Researcher at University College London
Publications - 60
Citations - 3105
Ernest B. Cady is an academic researcher from University College London. The author has contributed to research in topics: Neonatal encephalopathy & Phosphocreatine. The author has an hindex of 31, co-authored 60 publications receiving 2905 citations. Previous affiliations of Ernest B. Cady include University College London Hospitals NHS Foundation Trust.
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Journal ArticleDOI
Cerebral Magnetic Resonance Biomarkers in Neonatal Encephalopathy: A Meta-analysis
Sudhin Thayyil,M Chandrasekaran,Andrew M. Taylor,Alan Bainbridge,Ernest B. Cady,W. K. Kling Chong,Shahed Murad,Rumana Z Omar,Nicola J. Robertson +8 more
TL;DR: Deep gray matter Lac/NAA is the most accurate quantitative MR biomarker within the neonatal period for prediction of neurodevelopmental outcome after NE, and may be useful in early clinical management decisions and counseling parents and as a surrogate end point in clinical trials that evaluate novel neuroprotective therapies.
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Melatonin augments hypothermic neuroprotection in a perinatal asphyxia model
Nicola J. Robertson,Stuart Faulkner,Bobbi Fleiss,Bobbi Fleiss,Bobbi Fleiss,Alan Bainbridge,Csilla Andorka,D Price,Elizabeth M. Powell,Lucy Lecky-Thompson,Laura Thei,M Chandrasekaran,Mariya Hristova,Ernest B. Cady,Pierre Gressens,Pierre Gressens,Pierre Gressens,Xavier Golay,Gennadij Raivich +18 more
TL;DR: The safety and improved neuroprotection with a combination of melatonin with cooling support phase II clinical trials in infants with moderate and severe neonatal encephalopathy is confirmed.
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Moderate hypothermia within 6 h of birth plus inhaled xenon versus moderate hypothermia alone after birth asphyxia (TOBY-Xe): a proof-of-concept, open-label, randomised controlled trial
Denis Azzopardi,Nicola J. Robertson,Alan Bainbridge,Ernest B. Cady,Geoffrey Charles-Edwards,Aniko Deierl,Gianlorenzo Fagiolo,Nicholas P. Franks,James Griffiths,Jo Hajnal,Edmund Juszczak,Basil Kapetanakis,Louise Linsell,Mervyn Maze,Omar Omar,Brenda Strohm,Nora Tusor,David Edwards +17 more
TL;DR: Administration of xenon within the delayed timeframe used in this trial is feasible and apparently safe, but is unlikely to enhance the neuroprotective effect of cooling after birth asphyxia.
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The estimation of local brain temperature by in vivo 1H magnetic resonance spectroscopy.
TL;DR: Two methods for estimating temperature using 1H magnetic resonance spectroscopy are described: a partially water‐suppressed binomial sequence and non‐water‐suppression point‐resolved spectroscopic.
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Relation between delayed impairment of cerebral energy metabolism and infarction following transient focal hypoxia-ischaemia in the developing brain.
TL;DR: There was a significant relation between the extent of the delayed impairment of energy metabolism and the magnitude of the cerebral infarction (P<0.001) and Transient focal hypoxia-ischaemia in the 14-day-old rat leads to a biphasic disruption of cerebral energy metabolism.