B
Bobbi Fleiss
Researcher at RMIT University
Publications - 86
Citations - 3838
Bobbi Fleiss is an academic researcher from RMIT University. The author has contributed to research in topics: Neuroinflammation & Neuroprotection. The author has an hindex of 28, co-authored 84 publications receiving 3093 citations. Previous affiliations of Bobbi Fleiss include Monash University, Clayton campus & King's College London.
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Journal ArticleDOI
Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro.
Vibol Chhor,Tifenn Le Charpentier,Tifenn Le Charpentier,Sophie Lebon,Sophie Lebon,Marie-Virgine Oré,Marie-Virgine Oré,Idoia Lara Celador,Julien Josserand,Julien Josserand,Vincent Degos,Vincent Degos,Etienne Jacotot,Henrik Hagberg,Henrik Hagberg,Karin Sävman,Carina Mallard,Pierre Gressens,Bobbi Fleiss +18 more
TL;DR: A unique catalogue of phenotype markers and neuronotoxic effects of polarised primary microglia, as a comparative tool to screen neurotherapies, is presented.
Journal ArticleDOI
Systemic inflammation disrupts the developmental program of white matter
Géraldine Favrais,Yohan van de Looij,Bobbi Fleiss,Nelina Ramanantsoa,Nelina Ramanantsoa,Philippe Bonnin,Gisela Stoltenburg-Didinger,Adrien Lacaud,Elie Saliba,Olaf Dammann,Olaf Dammann,Olaf Dammann,Jorge Gallego,Jorge Gallego,Stéphane Sizonenko,Henrik Hagberg,Henrik Hagberg,Vincent Lelievre,Pierre Gressens +18 more
TL;DR: The goal of the present study was to test the hypothesis that moderate systemic inflammation is sufficient to alter white matter development.
Journal ArticleDOI
Tertiary mechanisms of brain damage: a new hope for treatment of cerebral palsy?
Bobbi Fleiss,Pierre Gressens +1 more
TL;DR: It is suggested that tertiary mechanisms of damage might include persistent inflammation and epigenetic changes that are implicit in prevention of endogenous repair and regeneration and predispose patients to development of future cognitive dysfunction and sensitisation to further injury.
Journal ArticleDOI
Melatonin augments hypothermic neuroprotection in a perinatal asphyxia model
Nicola J. Robertson,Stuart Faulkner,Bobbi Fleiss,Bobbi Fleiss,Bobbi Fleiss,Alan Bainbridge,Csilla Andorka,D Price,Elizabeth M. Powell,Lucy Lecky-Thompson,Laura Thei,M Chandrasekaran,Mariya Hristova,Ernest B. Cady,Pierre Gressens,Pierre Gressens,Pierre Gressens,Xavier Golay,Gennadij Raivich +18 more
TL;DR: The safety and improved neuroprotection with a combination of melatonin with cooling support phase II clinical trials in infants with moderate and severe neonatal encephalopathy is confirmed.
Journal ArticleDOI
Systemic stimulation of TLR2 impairs neonatal mouse brain development
Xiaonan Du,Bobbi Fleiss,Hongfu Li,Hongfu Li,Barbara D'Angelo,Yanyan Sun,Yanyan Sun,Changlian Zhu,Changlian Zhu,Henrik Hagberg,Henrik Hagberg,Ofer Levy,Carina Mallard,Xiaoyang Wang,Xiaoyang Wang +14 more
TL;DR: Repeated systemic exposure to the TLR2 agonist Pam3CSK4 can have a short-term negative impact on the neonatal mouse brain, although long-term memory function and the volume of gray or white matter are not affected.