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Esther Steidl
Publications - 8
Citations - 461
Esther Steidl is an academic researcher. The author has contributed to research in topics: Genetically modified mouse & Receptor. The author has an hindex of 7, co-authored 8 publications receiving 373 citations.
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Journal ArticleDOI
Easy-to-fabricate conducting polymer microelectrode arrays
Michele Sessolo,Dion Khodagholy,Jonathan Rivnay,Fabien Maddalena,Melanie Gleyzes,Esther Steidl,Bruno Buisson,George G. Malliaras +7 more
TL;DR: These MEAs allow in vitro recording of action potentials from rat hippocampus slices thanks to the low impedance of poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate) (PEDOT:PSS) electrodes.
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Phosphodiesterase 10A Inhibition Improves Cortico-Basal Ganglia Function in Huntington’s Disease Models
Vahri Beaumont,Sheng Zhong,Hai Lin,WenJin Xu,Amyaouch Bradaia,Esther Steidl,Melanie Gleyzes,Kristian Wadel,Bruno Buisson,Fernando E. Padovan-Neto,Shreaya Chakroborty,Karen M. Ward,John F. Harms,Jose Beltran,Mei Kwan,Afshin Ghavami,Jenny Häggkvist,Miklós Tóth,Christer Halldin,Andrea Varrone,Christoph Schaab,J. Nikolaj Dybowski,Sarah Elschenbroich,Kimmo Lehtimäki,Taneli Heikkinen,Larry Park,Jim Rosinski,Ladislav Mrzljak,Daniel J. Lavery,Anthony R. West,Christopher J. Schmidt,Margaret M. Zaleska,Ignacio Munoz-Sanjuan +32 more
TL;DR: The benefit of pharmacologic PDE10 inhibition to acutely correct basal ganglia circuitry deficits is demonstrated and restored corticostriatal input and boosted cortically driven indirect pathway activity.
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Myotonic dystrophy CTG expansion affects synaptic vesicle proteins, neurotransmission and mouse behaviour
Oscar Hernández-Hernández,Céline Guiraud-Dogan,Géraldine Sicot,Aline Huguet,Sabrina Luilier,Esther Steidl,Stefanie Saenger,Elodie Marciniak,Hélène Obriot,Caroline Chevarin,Annie Nicole,Lucile Revillod,Konstantinos Charizanis,Kuang-Yung Lee,Kuang-Yung Lee,Yasuhiro Suzuki,Takashi Kimura,Tohru Matsuura,Bulmaro Cisneros,Maurice S. Swanson,F. Trovero,Bruno Buisson,Jean-Charles Bizot,Michel Hamon,Sandrine Humez,Guillaume Bassez,Friedrich Metzger,Luc Buée,Arnold Munnich,Nicolas Sergeant,Geneviève Gourdon,Mário Gomes-Pereira +31 more
TL;DR: A novel connection between physiological phenotypes and synaptic protein dysregulation, indicative of synaptic dysfunction in myotonic dystrophy type 1 brain pathology is found.
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The novel KMO inhibitor CHDI-340246 leads to a restoration of electrophysiological alterations in mouse models of Huntington's disease.
Vahri Beaumont,Ladislav Mrzljak,Ulrike Dijkman,Robert Freije,Mariette Heins,Arash Rassoulpour,Geoffrey Tombaugh,Simon Gelman,Amyaouch Bradaia,Esther Steidl,Melanie Gleyzes,Taneli Heikkinen,Kimmo Lehtimäki,Jukka Puoliväli,Outi Kontkanen,Robyn M. Javier,Ioana Neagoe,Heike Deisemann,Dirk Winkler,Andreas Ebneth,Vinod Khetarpal,Leticia Toledo-Sherman,Celia Dominguez,Larry Park,Ignacio Munoz-Sanjuan +24 more
TL;DR: It is demonstrated that the chronic dosing of a selective KMO inhibitor does not significantly modify behavioral phenotypes or natural progression in mouse models of HD.
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MPX-004 and MPX-007: New Pharmacological Tools to Study the Physiology of NMDA Receptors Containing the GluN2A Subunit.
Volkmann Robert A,Christopher Fanger,David E. Anderson,Venkata Ramana Sirivolu,Kathy Paschetto,Earl Gordon,Caterina Virginio,Melanie Gleyzes,Bruno Buisson,Esther Steidl,Susanna B. Mierau,Michela Fagiolini,Frank S. Menniti +12 more
TL;DR: GluN2A-selectivity at native receptors was confirmed by the finding that MPX-004 had no inhibitory effect on NMDA receptor mediated synaptic currents in cortical slices from GRIN2A knock out mice.