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Eszter K. Vladar
Researcher at University of Colorado Denver
Publications - 54
Citations - 2421
Eszter K. Vladar is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 19, co-authored 38 publications receiving 1788 citations. Previous affiliations of Eszter K. Vladar include University of Colorado Boulder & Anschutz Medical Campus.
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Journal ArticleDOI
Planar Cell Polarity Signaling: The Developing Cell’s Compass
TL;DR: In this paper, the authors discuss similarities and differences in the mechanism that controls PCP as it has been adapted to a broad variety of morphological cellular asymmetries in various organisms, as well as discuss the differences between the two mechanisms.
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Microtubules Enable the Planar Cell Polarity of Airway Cilia
TL;DR: It is shown that basal bodies dock after polarity of PCP proteins is established and are polarized nearly simultaneously, and that refinement of basal body/cilium orientation continues during airway epithelial development.
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Multicilin promotes centriole assembly and ciliogenesis during multiciliate cell differentiation
TL;DR: Findings indicate that multicilin initiates multiciliate cell differentiation in diverse tissues, by coordinately promoting the transcriptional changes required for motile ciliogenesis and centriole assembly.
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A Homozygous Mutation in Human PRICKLE1 Causes an Autosomal-Recessive Progressive Myoclonus Epilepsy-Ataxia Syndrome
Alexander G. Bassuk,Robyn H. Wallace,Aimee Buhr,Andrew R. Buller,Zaid Afawi,Masahito Shimojo,Shingo Miyata,Shan Chen,Pedro Gonzalez-Alegre,Hilary L. Griesbach,Shu Wu,Marcus B. Nashelsky,Eszter K. Vladar,Dragana Antic,Polly J. Ferguson,Sebahattin Cirak,Thomas Voit,Matthew P. Scott,Jeffrey D. Axelrod,Christina A. Gurnett,Azhar S. Daoud,Sara Kivity,Miriam Y. Neufeld,Aziz Mazarib,Rachel Straussberg,Simri Walid,Amos D. Korczyn,Diane C. Slusarski,Samuel F. Berkovic,Hatem El-Shanti,Hatem El-Shanti +30 more
TL;DR: A mutation in PRICKLE1 is identified (also known as RILP for REST/NRSF interacting LIM domain protein) in all three of these pedigrees of individuals with PME and ataxia, and is the first molecule in the noncanonical WNT signaling pathway to be directly implicated in human epilepsy.
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Molecular characterization of centriole assembly in ciliated epithelial cells
Eszter K. Vladar,Tim Stearns +1 more
TL;DR: This system will help determine the mechanism of centrioles formation in mammalian cells and how the limitation on centriole duplication is overcome in ciliated epithelial cells.