Eugen Faist

TL;DR: In this article, the predictive potential of circulating free DNA/neutrophil extracellular traps (cf-DNA/NETs) for mortality in patients with severe burn injury was reported.

TL;DR: Males are more susceptible to multiple organ failure, sepsis, and mortality after trauma and Females aged 16 to 44 years seem to tolerate shock better, and differences were not exclusively related to reproductive age and thus cannot be attributed to sex hormones alone.

TL;DR: Clinical relevant principles of compound transport and the experimental and clinical effects of hemofiltration during sepsis are reviewed and modern strategies of blood purification that may be associated with a high degree of effectiveness for mediator removal (high-volume hem ofiltration and heparin-induced extracorporeal lipoprotein-fibrinogen precipitation) are discussed.

TL;DR: It is shown that an immunomodulatory therapy can influence alterations in immune mechanisms after cardiopulmonary bypass and additional administration of thymopentin significantly reduced elevated interleukin-6 synthesis.

TL;DR: There was no correlation between serum concentrations of the mediators investigated and susceptibility to complications or outcome, but persistently high concentrations of IL-8, ENA-78, and sP-selectin were found during recovery from the injuries, but sE- selectin was increased only during the first week after major trauma.