M
Martin Sauer
Researcher at Hochschule Hannover
Publications - 165
Citations - 4401
Martin Sauer is an academic researcher from Hochschule Hannover. The author has contributed to research in topics: Transplantation & Hematopoietic stem cell transplantation. The author has an hindex of 23, co-authored 141 publications receiving 3553 citations. Previous affiliations of Martin Sauer include Takata Corporation & University of Minnesota.
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Journal ArticleDOI
Inflammatory bowel disease and mutations affecting the interleukin-10 receptor.
Erik-Oliver Glocker,Daniel Kotlarz,Kaan Boztug,E. Michael Gertz,Alejandro A. Schäffer,Fatih Noyan,Mario Perro,Jana Diestelhorst,Anna Allroth,Dhaarini Murugan,Nadine Hätscher,Dietmar Pfeifer,Karl-Walter Sykora,Martin Sauer,Hans Kreipe,Martin Lacher,Rainer Nustede,Cristina Woellner,Ulrich Baumann,Ulrich Salzer,Sibylle Koletzko,Neil Shah,Anthony W. Segal,Axel Sauerbrey,Stephan Buderus,Scott B. Snapper,Bodo Grimbacher,Christoph Klein +27 more
TL;DR: Mutations in genes encoding the IL10R subunit proteins were found in patients with early-onset enterocolitis, involving hyperinflammatory immune responses in the intestine, and resulted in disease remission in one patient.
Journal ArticleDOI
GDF-15 is an inhibitor of leukocyte integrin activation required for survival after myocardial infarction in mice
Tibor Kempf,Alexander Zarbock,Christian Widera,Stefan Butz,Anika Stadtmann,Jan Rossaint,Matteo Bolomini-Vittori,Mortimer Korf-Klingebiel,L. Christian Napp,Birte Hansen,Anna Kanwischer,Udo Bavendiek,Gernot Beutel,Martin Hapke,Martin Sauer,Carlo Laudanna,Nancy Hogg,Dietmar Vestweber,Kai C. Wollert +18 more
TL;DR: GDF-15 is the first cytokine identified as an inhibitor of PMN recruitment by direct interference with chemokine signaling and integrin activation, and loss of this anti-inflammatory mechanism leads to fatal cardiac rupture after myocardial infarction.
Journal ArticleDOI
Loss of interleukin-10 signaling and infantile inflammatory bowel disease: implications for diagnosis and therapy.
Daniel Kotlarz,Daniel Kotlarz,Rita Beier,Dhaarini Murugan,Dhaarini Murugan,Jana Diestelhorst,Jana Diestelhorst,Ole Jensen,Ole Jensen,Kaan Boztug,Dietmar Pfeifer,Hans Kreipe,Eva Doreen Pfister,Ulrich Baumann,Jacek Puchałka,Jens Bohne,Odul Egritas,Buket Dalgic,Kaija-Leena Kolho,Axel Sauerbrey,Stephan Buderus,Tayfun Güngör,Axel Enninger,Yu Kar Ling Koda,Graziella Guariso,Batia Weiss,Selim Corbacioglu,Piotr Socha,Nuray Uslu,Ayse Metin,Ghassan Wahbeh,Khalid Husain,Dina Ramadan,Waleed Al Herz,Bodo Grimbacher,Martin Sauer,Karl Walter Sykora,Sibylle Koletzko,Christoph Klein,Christoph Klein +39 more
TL;DR: It is indicated that infantile IBD patients with perianal disease should be screened for IL-10 and IL-11R deficiency and that allogeneic HSCT can induce remission in those with IL- 10R deficiency.
Journal ArticleDOI
Long-term follow-up of IPEX syndrome patients after different therapeutic strategies: An international multicenter retrospective study
Federica Barzaghi,Laura C. Amaya Hernandez,Benedicte Neven,Silvia Ricci,Zeynep Yesim Kucuk,Jack J. Bleesing,Zohreh Nademi,Mary Slatter,Erlinda R. Ulloa,Anna Shcherbina,Anna Roppelt,Austen Worth,Juliana Silva,Alessandro Aiuti,Luis Murguia-Favela,Carsten Speckmann,Magda Carneiro-Sampaio,Juliana Folloni Fernandes,Safa Baris,Ahmet Ozen,Elif Karakoc-Aydiner,Ayca Kiykim,Ansgar Schulz,Sandra Steinmann,Lucia Dora Notarangelo,Eleonora Gambineri,Paolo Lionetti,William T. Shearer,Lisa R. Forbes,Caridad Martinez,Despina Moshous,Stéphane Blanche,Alain Fisher,Frank M. Ruemmele,Come Tissandier,Marie Ouachée-Chardin,Frédéric Rieux-Laucat,Marina Cavazzana,Waseem Qasim,Barbarella Lucarelli,Michael H. Albert,Ichiro Kobayashi,Laura C. Alonso,Cristina Díaz de Heredia,Hirokazu Kanegane,Anita Lawitschka,Jong Jin Seo,Marta González-Vicent,Miguel Angel Diaz,Rakesh K. Goyal,Martin Sauer,Akif Yesilipek,Minsoo Kim,Yesim Yilmaz-Demirdag,Monica Bhatia,Julie Khlevner,Erick J. Richmond Padilla,Silvana Martino,Davide Montin,Olaf Neth,Agueda Molinos-Quintana,Justo Valverde-Fernandez,Arnon Broides,Vered Pinsk,Antje Ballauf,Filomeen Haerynck,Victoria Bordon,Catharina Dhooge,Maria Laura Garcia-Lloret,Robbert G. M. Bredius,Krzysztof Kałwak,Elie Haddad,Markus G. Seidel,Gregor Dückers,Sung-Yun Pai,Sung-Yun Pai,Christopher C. Dvorak,Stephan Ehl,Franco Locatelli,Frederick D. Goldman,Andrew R. Gennery,M.J. Cowan,Maria Grazia Roncarolo,Rosa Bacchetta +83 more
TL;DR: Patients receiving chronic IS were hampered by disease recurrence or complications, impacting long‐term disease‐free survival, and when performed in patients with a low OI score, HSCT resulted in disease resolution with better quality of life, independent of age, donor source, or conditioning regimen.
Journal ArticleDOI
The influence of residual neuromuscular block on the incidence of critical respiratory events. A randomised, prospective, placebo-controlled trial.
TL;DR: In this randomised, prospective, placebo-controlled trial, minimal residual block was associated with hypoxaemia in the post-anaesthesia care unit and neostigmine 20 &mgr;g kg−1 was effective in antagonising rocuronium-induced (minimal) blockade.