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Eulàlia Martí
Researcher at University of Barcelona
Publications - 80
Citations - 4838
Eulàlia Martí is an academic researcher from University of Barcelona. The author has contributed to research in topics: Gene silencing & Hippocampal formation. The author has an hindex of 33, co-authored 74 publications receiving 4364 citations. Previous affiliations of Eulàlia Martí include Universidad Miguel Hernández de Elche & University of Cantabria.
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Journal ArticleDOI
MicroRNA profiling of Parkinson’s disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function
Elena Miñones-Moyano,Sílvia Porta,Geòrgia Escaramís,Raquel Rabionet,Susana Iraola,Birgit Kagerbauer,Yolanda Espinosa-Parrilla,Isidre Ferrer,Isidre Ferrer,Xavier Estivill,Eulàlia Martí +10 more
TL;DR: It is proposed that early deregulation of miR-34b/c in PD triggers downstream transcriptome alterations underlying mitochondrial dysfunction and oxidative stress, which ultimately compromise cell viability.
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BDNF and full-length and truncated TrkB expression in Alzheimer disease. Implications in therapeutic strategies.
Isidro Ferrer,Conxita Marín,Ma. Jesús (Maria Jesús) Buxó Rey,Teresa Ribalta,E Goutan,Rosa Blanco,Eduard Tolosa,Eulàlia Martí +7 more
TL;DR: The present results demonstrate selective decline of the BDNF/TrkB neurotrophic signaling pathway in the frontal cortex and hippocampus in AD and provide supplemental data that may be relevant in discussing the suitability of the use of BDNF as a therapeutic agent in patients with AD.
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Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down’s syndrome
Xavier Altafaj,Mara Dierssen,Carmela Baamonde,Eulàlia Martí,Joana Visa,Jordi Guimerà,Marta Oset,Juan R. González,Jesús Flórez,Cristina Fillat,Xavier Estivill +10 more
TL;DR: Transgenic mice generated by overexpressing the full-length cDNA of Dyrk1A show alterations comparable with those found in the partial trisomy chromosome 16 murine models of DS and suggest a causative role of DYRK1A in mental retardation and in motor anomalies of DS.
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Dyrk1A Haploinsufficiency Affects Viability and Causes Developmental Delay and Abnormal Brain Morphology in Mice
Vassiliki Fotaki,Mara Dierssen,Soledad Alcántara,Salvador Martinez,Eulàlia Martí,Caty Casas,Joana Visa,Eduardo Soriano,Xavier Estivill,Maria L. Arbonés +9 more
TL;DR: Evidence is provided about the nonredundant, vital role of Dyrk1A and a conserved mode of action is suggested that determines normal growth and brain size in both mice and flies.
Journal ArticleDOI
A myriad of miRNA variants in control and Huntington’s disease brain regions detected by massively parallel sequencing
Eulàlia Martí,Lorena Pantano,Mónica Bañez-Coronel,Franc Llorens,Elena Miñones-Moyano,Sílvia Porta,Lauro Sumoy,Isidre Ferrer,Xavier Estivill +8 more
TL;DR: The results show that miRNA variability is a ubiquitous phenomenon in the adult human brain, which may influence gene expression in physiological and pathological conditions.