F
Fabienne De Backer
Researcher at Université catholique de Louvain
Publications - 17
Citations - 2409
Fabienne De Backer is an academic researcher from Université catholique de Louvain. The author has contributed to research in topics: Gut flora & Prebiotic. The author has an hindex of 14, co-authored 17 publications receiving 2164 citations. Previous affiliations of Fabienne De Backer include Catholic University of Leuven.
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Journal ArticleDOI
Gut microbiota fermentation of prebiotics increases satietogenic and incretin gut peptide production with consequences for appetite sensation and glucose response after a meal
Patrice D. Cani,Elodie Lecourt,Evelyne M. Dewulf,Florence M. Sohet,Barbara D. Pachikian,Damien Naslain,Fabienne De Backer,Audrey M. Neyrinck,Nathalie M. Delzenne +8 more
TL;DR: Prebiotic supplementation was associated with an increase in plasma gut peptide concentrations (glucagon-like peptide 1 and peptide YY), which may contribute in part to changes in appetite sensation and glucose excursion responses after a meal in healthy subjects.
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Prebiotic Effects of Wheat Arabinoxylan Related to the Increase in Bifidobacteria, Roseburia and Bacteroides/Prevotella in Diet-Induced Obese Mice
Audrey M. Neyrinck,Sam Possemiers,Céline Druart,Tom Van de Wiele,Fabienne De Backer,Patrice D. Cani,Yvan Larondelle,Nathalie M. Delzenne +7 more
TL;DR: In this article, the ability of a specific concentrate of water-extractable high molecular weight arabinoxylans (AX) from wheat to modulate both the gut microbiota and lipid metabolism in high-fat (HF) diet-induced obese mice was investigated.
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Dietary modulation of clostridial cluster XIVa gut bacteria (Roseburia spp.) by chitin–glucan fiber improves host metabolic alterations induced by high-fat diet in mice
Audrey M. Neyrinck,Sam Possemiers,Willy Verstraete,Fabienne De Backer,Patrice D. Cani,Nathalie M. Delzenne +5 more
TL;DR: The findings support the view that chronic consumption of CG has potential beneficial effects with respect to the development of obesity and associated metabolic diabetes and hepatic steatosis, through a mechanism related to the restoration of the composition and/or the activity of gut bacteria, namely, bacteria from clostridial cluster XIVa.
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Polyphenol-rich extract of pomegranate peel alleviates tissue inflammation and hypercholesterolaemia in high-fat diet-induced obese mice: potential implication of the gut microbiota
Audrey M. Neyrinck,Vincent F. Van Hée,Laure B. Bindels,Fabienne De Backer,Patrice D. Cani,Nathalie M. Delzenne +5 more
TL;DR: PPE supplementation counteracted the HF-induced expression of inflammatory markers both in the colon and the visceral adipose tissue and support that pomegranate constitutes a promising food in the control of atherogenic and inflammatory disorders associated with diet-induced obesity.
Journal ArticleDOI
Restoring specific lactobacilli levels decreases inflammation and muscle atrophy markers in an acute leukemia mouse model
Laure B. Bindels,Raphaël Beck,Olivier Schakman,Jennifer C. Martin,Fabienne De Backer,Florence M. Sohet,Evelyne M. Dewulf,Barbara D. Pachikian,Audrey M. Neyrinck,Jean-Paul Thissen,Julien Verrax,Pedro Buc Calderon,Bruno Pot,Corinne Grangette,Patrice D. Cani,Karen P. Scott,Nathalie M. Delzenne +16 more
TL;DR: The results suggest that the gut microbiota could constitute a novel therapeutic target in the management of leukemia-associated inflammation and related disorders in the muscle.