F
Fabrício Rios-Santos
Researcher at Universidade Federal de Mato Grosso
Publications - 36
Citations - 1656
Fabrício Rios-Santos is an academic researcher from Universidade Federal de Mato Grosso. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 17, co-authored 29 publications receiving 1483 citations. Previous affiliations of Fabrício Rios-Santos include University of São Paulo & State University of Santa Cruz.
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Journal ArticleDOI
The Genomic Ancestry of Individuals from Different Geographical Regions of Brazil Is More Uniform Than Expected
Sérgio D.J. Pena,Giuliano Di Pietro,Mateus Fuchshuber-Moraes,Julia P. Genro,Mara H. Hutz,Fernanda S G Kehdy,Fabiana B. Kohlrausch,Luiz Alexandre V. Magno,Raquel Carvalho Montenegro,Manoel Odorico de Moraes,Maria Elisabete Amaral de Moraes,Milene Raiol de Moraes,Elida B. Ojopi,Jamila Alessandra Perini,Clarice Racciopi,Ândrea Ribeiro-dos-Santos,Fabrício Rios-Santos,Marco Aurélio Romano-Silva,Vinicius A. Sortica,Guilherme Suarez-Kurtz +19 more
TL;DR: It is proposed that the immigration of six million Europeans to Brazil in the 19th and 20th centuries is in large part responsible for dissipating previous ancestry dissimilarities that reflected region-specific population histories.
Journal ArticleDOI
Glutathione S-transferases: an overview in cancer research.
TL;DR: Up-to-date information about the new generation of GST-activated cytotoxic prodrugs based on GST overexpression in tumor-acquired drug resistance and the newest results of clinical trials are presented.
Journal ArticleDOI
Consistent interethnic differences in the distribution of clinically relevant endothelial nitric oxide synthase genetic polymorphisms.
Aline S. Marroni,Ingrid F. Metzger,Debora C. Souza-Costa,Sabrina Nagassaki,Valeria C. Sandrim,Ronan Xavier Corrêa,Fabrício Rios-Santos,Jose E. Tanus-Santos +7 more
TL;DR: A consistent difference in the distribution of eNOS genetic variants in blacks compared with whites is strongly suggested and indicates that the interethnic differences do not vary with geographic origin.
Journal ArticleDOI
Down-regulation of CXCR2 on Neutrophils in Severe Sepsis Is Mediated by Inducible Nitric Oxide Synthase–derived Nitric Oxide
Fabrício Rios-Santos,José C. Alves-Filho,Fabricio O. Souto,Fernando Spiller,Andressa de Freitas,Celina Monteiro da Cruz Lotufo,Milena Botelho Pereira Soares,Ricardo Ribeiro dos Santos,Mauro M. Teixeira,Fernando Q. Cunha +9 more
TL;DR: Results highlight evidences that the failure of neutrophils to migrate to an infection focus during severe sepsis is associated with excessive NO production and NO-dependent regulation of the expression of CXCR2 on the neutrophil surface.
Journal ArticleDOI
Vitexin reduces neutrophil migration to inflammatory focus by down-regulating pro-inflammatory mediators via inhibition of p38, ERK1/2 and JNK pathway
Suellen Iara Guirra Rosa,Fabrício Rios-Santos,Sikiru Olaitan Balogun,Domingos Tabajara de Oliveira Martins +3 more
TL;DR: Vitexin had low cytotoxicity and was able to reduce the releases of TNF-α, IL-1β, NO, PGE2 and increase in IL-10 release by LPS activated RAW 264.7 cells.