M
Mara H. Hutz
Researcher at Universidade Federal do Rio Grande do Sul
Publications - 295
Citations - 9617
Mara H. Hutz is an academic researcher from Universidade Federal do Rio Grande do Sul. The author has contributed to research in topics: Population & Attention deficit hyperactivity disorder. The author has an hindex of 47, co-authored 293 publications receiving 8886 citations. Previous affiliations of Mara H. Hutz include Johns Hopkins University School of Medicine & Federal University of Pará.
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Journal ArticleDOI
The Genomic Ancestry of Individuals from Different Geographical Regions of Brazil Is More Uniform Than Expected
Sérgio D.J. Pena,Giuliano Di Pietro,Mateus Fuchshuber-Moraes,Julia P. Genro,Mara H. Hutz,Fernanda S G Kehdy,Fabiana B. Kohlrausch,Luiz Alexandre V. Magno,Raquel Carvalho Montenegro,Manoel Odorico de Moraes,Maria Elisabete Amaral de Moraes,Milene Raiol de Moraes,Elida B. Ojopi,Jamila Alessandra Perini,Clarice Racciopi,Ândrea Ribeiro-dos-Santos,Fabrício Rios-Santos,Marco Aurélio Romano-Silva,Vinicius A. Sortica,Guilherme Suarez-Kurtz +19 more
TL;DR: It is proposed that the immigration of six million Europeans to Brazil in the 19th and 20th centuries is in large part responsible for dissipating previous ancestry dissimilarities that reflected region-specific population histories.
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Assessing individual interethnic admixture and population substructure using a 48-insertion-deletion (INSEL) ancestry-informative marker (AIM) panel.
Ney Pereira Carneiro dos Santos,Elzemar Martins Ribeiro-Rodrigues,Ândrea Ribeiro-dos-Santos,Rui Pereira,Rui Pereira,Leonor Gusmão,António Amorim,João Farias Guerreiro,Marco Antônio Zago,Cecilia Helena Fricke Matte,Mara H. Hutz,Sidney Santos +11 more
TL;DR: The ability to accurately infer interethnic admixtures highlights the usefulness of this marker set for assessing population substructure in association studies, particularly those conducted in Brazilian and other Latin American populations sharing trihybrid ancestry patterns.
Journal ArticleDOI
Y-Chromosome Evidence for Differing Ancient Demographic Histories in the Americas
Maria Cátira Bortolini,Francisco Mauro Salzano,Mark G. Thomas,Steven Stuart,Selja P. K. Nasanen,Claiton H.D. Bau,Mara H. Hutz,Zulay Layrisse,Maria Luiza Petzl-Erler,Luiza T. Tsuneto,Kim Hill,A. M. Hurtado,Dinorah C. Castro-de-Guerra,Maria Mercedes Torres,Helena Groot,Roman Michalski,Pagbajabyn Nymadawa,Gabriel Bedoya,Neil Bradman,Damian Labuda,Andres Ruiz-Linares,Andres Ruiz-Linares +21 more
TL;DR: Age estimates based on Y-chromosome microsatellite diversity place the initial settlement of the American continent at approximately 14,000 years ago, in relative agreement with the age of well-established archaeological evidence.
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The role of common variants of ABCB1, CYP3A4, and CYP3A5 genes in lipid-lowering efficacy and safety of simvastatin treatment.
Marilu Fiegenbaum,Fabiano Roldao Silveira,Cézar Roberto Van der Sand,Luiz Carlos Van der Sand,Maria Elvira Wagner Ferreira,Renan Canibal Pires,Mara H. Hutz +6 more
TL;DR: The objective was to investigate the interactions between common polymorphisms in ABCB1, CYP3A4, and CYP 3A5 genes and the lipid‐lowering efficacy and safety of the 3‐hydroxy‐3‐methylglutaryl‐coenzyme A reductase inhibitor simvastatin.
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Attention-deficit hyperactivity disorder: a study of association with both the dopamine transporter gene and the dopamine D4 receptor gene.
Tatiana Roman,Marcelo Schmitz,Guilherme V. Polanczyk,Mariana Eizirik,Luis Augusto Rohde,Mara H. Hutz +5 more
TL;DR: An interaction effect of both genes on ADHD hyperactive/impulsive dimension was observed, adding to the group of studies that together suggest a small effect of these genes in the susceptibility to ADHD.