M
Manoel Odorico de Moraes
Researcher at Federal University of Ceará
Publications - 356
Citations - 9986
Manoel Odorico de Moraes is an academic researcher from Federal University of Ceará. The author has contributed to research in topics: Cytotoxicity & Apoptosis. The author has an hindex of 48, co-authored 341 publications receiving 8776 citations. Previous affiliations of Manoel Odorico de Moraes include Federal University of Rio de Janeiro & Federal University of São Carlos.
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Journal ArticleDOI
The Genomic Ancestry of Individuals from Different Geographical Regions of Brazil Is More Uniform Than Expected
Sérgio D.J. Pena,Giuliano Di Pietro,Mateus Fuchshuber-Moraes,Julia P. Genro,Mara H. Hutz,Fernanda S G Kehdy,Fabiana B. Kohlrausch,Luiz Alexandre V. Magno,Raquel Carvalho Montenegro,Manoel Odorico de Moraes,Maria Elisabete Amaral de Moraes,Milene Raiol de Moraes,Elida B. Ojopi,Jamila Alessandra Perini,Clarice Racciopi,Ândrea Ribeiro-dos-Santos,Fabrício Rios-Santos,Marco Aurélio Romano-Silva,Vinicius A. Sortica,Guilherme Suarez-Kurtz +19 more
TL;DR: It is proposed that the immigration of six million Europeans to Brazil in the 19th and 20th centuries is in large part responsible for dissipating previous ancestry dissimilarities that reflected region-specific population histories.
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Studies of the anticancer potential of plants used in Bangladeshi folk medicine.
Letícia V. Costa-Lotufo,Mahmud Tareq Hassan Khan,Arjumand Ather,Diego Veras Wilke,Paula C. Jimenez,Cláudia Pessoa,Maria Elisabete Amaral de Moraes,Manoel Odorico de Moraes +7 more
TL;DR: In conclusion, among all tested extracts, only the extracts of Oroxylum indicum, Moringa oleifera and Aegles marmelos could be considered as potential sources of anticancer compounds.
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Overview of the therapeutic potential of piplartine (piperlongumine).
Daniel P. Bezerra,Cláudia Pessoa,Manoel Odorico de Moraes,Nicolau Saker-Neto,E.R. Silveira,Letícia V. Costa-Lotufo +5 more
TL;DR: It is concluded that piplartine is effective for use in cancer therapy and its safety using chronic toxicological studies should be addressed to support the viability of clinical trials.
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In vivo growth-inhibition of Sarcoma 180 by piplartine and piperine, two alkaloid amides from Piper.
Daniel P. Bezerra,Fernanda Oliveira de Castro,Ana Paula Negreiros Nunes Alves,Cláudia Pessoa,Manoel Odorico de Moraes,E.R. Silveira,Mary Anne S. Lima,Francisca Juliana Martins Elmiro,Letícia V. Costa-Lotufo +8 more
TL;DR: Histopathological and morphological analyses of the tumor and the organs, including liver, spleen, and kidney, were performed in order to evaluate the toxicological aspects of the treatment with these amides and it was shown that both organs were reversibly affected by piplartine and piperine treatment, but in a different way.
Journal ArticleDOI
Cytotoxic activity of Brazilian Cerrado plants used in traditional medicine against cancer cell lines
Mariana Laundry de Mesquita,José Elias de Paula,Cláudia Pessoa,Manoel Odorico de Moraes,Letícia V. Costa-Lotufo,Raphaël Grougnet,Sylvie Michel,Francois Tillequin,Laila S. Espindola +8 more
TL;DR: To investigate the cytotoxic potential of 412 extracts from Brazilian Cerrado plants used in traditional medicine belonging to 21 families against tumor cell lines in culture,Bioassay-guided fractionation of the last extract led to the isolation of glaucarubinone, which showed pronounced activity against the four cell lines studied.