F
Fei Xiao
Researcher at Shanghai Jiao Tong University
Publications - 29
Citations - 660
Fei Xiao is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: RANKL & Osteoclast. The author has an hindex of 11, co-authored 22 publications receiving 465 citations.
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Journal ArticleDOI
The effect of metallic magnesium degradation products on osteoclast-induced osteolysis and attenuation of NF-κB and NFATc1 signaling.
Zanjing Zhai,Xinhua Qu,Haowei Li,Ke Yang,Peng Wan,Lili Tan,Zhengxiao Ouyang,Xuqiang Liu,Bo Tian,Fei Xiao,Wengang Wang,Chuan Jiang,Tingting Tang,Qiming Fan,An Qin,Kerong Dai +15 more
TL;DR: This study suggests that metallic magnesium, one of the orthopedic implants with superior properties, has significant potential for the treatment of osteolysis-related diseases caused by excessive osteoclast formation and function.
Journal ArticleDOI
Long noncoding RNA MALAT1 promotes osterix expression to regulate osteogenic differentiation by targeting miRNA-143 in human bone marrow-derived mesenchymal stem cells.
TL;DR: It is suggested that MALAT1 acts to regulate Osx expression through targeting miR‐143; thus, it is considered as a positive regulator in hBMSC osteogenic differentiation.
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Gremlin2 Suppression Increases the BMP-2-Induced Osteogenesis of Human Bone Marrow-Derived Mesenchymal Stem Cells Via the BMP-2/Smad/Runx2 Signaling Pathway.
Chenglong Wang,Fei Xiao,Chuandong Wang,Junfeng Zhu,Chao Shen,Bin Zuo,Hui Wang,De Li,X. Wang,Wei-Jia Feng,Zhuokai Li,Guoli Hu,Xiaoling Zhang,Xiaodong Chen +13 more
TL;DR: It was found that Grem2 expression was upregulated by BMP‐2 within the range of 0–1 μg/mL, and significant increases were evident at 48, 72, and 96 h after B MP‐2 treatment, whereas overexpression of Gremlin2 had the opposite trend.
Journal ArticleDOI
Effect of active arm swing to local dynamic stability during walking.
Yu Wu,Yue Li,Anmin Liu,Fei Xiao,Yin-Zhi Wang,Fei Hu,Jin-Ling Chen,Kerong Dai,Dong-Yun Gu,Dong-Yun Gu +9 more
TL;DR: Findings indicate that active arm swing may help to improve the local dynamic stability of the trunk segments in medial-lateral direction and in anterior-posterior and vertical direction.
Journal ArticleDOI
Geraniin suppresses RANKL-induced osteoclastogenesis in vitro and ameliorates wear particle-induced osteolysis in mouse model.
Fei Xiao,Zanjing Zhai,Chuan Jiang,Xuqiang Liu,Haowei Li,Xinhua Qu,Zhengxiao Ouyang,Qiming Fan,Tingting Tang,An Qin,Dongyun Gu,Dongyun Gu +11 more
TL;DR: It is demonstrated for the first time that geraniin, an active natural compound derived from Geranium thunbergii, ameliorated particle-induced osteolysis in a Ti particle- induced mouse calvaria model in vivo and the mechanism by which geraniIn exerts inhibitory effects on osteoclast differentiation in vitro is investigated.