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Flavia Bortolotti
Researcher at University of Padua
Publications - 129
Citations - 6065
Flavia Bortolotti is an academic researcher from University of Padua. The author has contributed to research in topics: Hepatitis & Hepatitis C. The author has an hindex of 37, co-authored 129 publications receiving 5859 citations. Previous affiliations of Flavia Bortolotti include University of Genoa & University of Pavia.
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Journal ArticleDOI
Natural history of chronic hepatitis B: Special emphasis on disease progression and prognostic factors
TL;DR: There is a growing understanding of viral, host and environmental factors influencing disease progression, which ultimately could improve the management of chronic hepatitis B.
Journal ArticleDOI
Seroconversion from hepatitis B e antigen to anti-HBe in chronic hepatitis B virus infection
Giuseppe Realdi,A. Alberti,Massimo Rugge,Flavia Bortolotti,A. M. Rigoli,Federico Tremolada,Arturo Ruol +6 more
TL;DR: In HB s Ag-positive chronic active hepatitis presence of HB e Ag in serum identifies an early, although prolonged, phase of active virus replication that is frequently followed by the disappearance of complete virus particles from serum and appearance of anti-HB e .
Journal ArticleDOI
Long-Term Course of Chronic Hepatitis C in Children: From Viral Clearance to End-Stage Liver Disease
Flavia Bortolotti,Gabriella Verucchi,Calogero Cammà,Giuseppe Cabibbo,Lucia Zancan,Giuseppe Indolfi,Raffaella Giacchino,Matilde Marcellini,Maria Grazia Marazzi,Cristiana Barbera,Giuseppe Maggiore,Pietro Vajro,S. Bartolacci,Fiorella Balli,Anna Maccabruni,Maria Guido +15 more
TL;DR: Over the course of a decade, few children with chronic HCV infection cleared viremia spontaneously, and those who did were more likely to have genotype 3, leading to end-stage liver disease in a small subgroup characterized by perinatal exposure, maternal drug use, and infection with HCV genotype 1a.
Journal ArticleDOI
Chronic hepatitis B in children after e antigen seroclearance: final report of a 29-year longitudinal study.
Flavia Bortolotti,Maria Guido,S. Bartolacci,Paolo Cadrobbi,Carlo Crivellaro,Franco Noventa,Giulia Morsica,Maria Moriondo,Angelo Gatta +8 more
TL;DR: The overall prognosis for chronic hepatitis B in horizontally infected Caucasian children is favorable; however, some patients progress to HCC and HBeAg‐negative hepatitis.
Journal ArticleDOI
Chronic hepatitis C virus infection in childhood: clinical patterns and evolution in 224 white children.
Paloma Jara,Massimo Resti,Loreto Hierro,Raffaella Giacchino,Cristiana Barbera,Lucia Zancan,Carlo Crivellaro,Etienne Sokal,Chiara Azzari,Maria Guido,Flavia Bortolotti +10 more
TL;DR: Pediatric HCV infection is usually mild, but few patients, especially those who are perinatally infected, clear viremia in the medium-term follow-up, and the higher rates of fibrosis observed in older patients suggest the possibility of an insidious progression of HCV-associated liver disease.