Flavia Cassiola

TL;DR: Left ventricular dysfunction might be due, in part, to direct cardiomyocyte toxicity, exacerbated by hypertension, and patients treated with sunitinib should be closely monitored for hypertension and LVEF reduction, especially those with a history of coronary artery disease or cardiac risk factors.

TL;DR: It is shown that accumulation of angiogenesis regulators in platelets of animals bearing malignant tumors exceeds significantly their concentration in plasma or serum, as well as their levels in Platelets from non-tumor-bearing animals.

TL;DR: A magnetic nanotechnology that activates a biochemical signalling mechanism normally switched on by binding of multivalent chemical ligands, and may represent a new actuator mechanism for cell-based microtechnologies and man-machine interfaces.

TL;DR: Lodamin is an oral nontoxic antiangiogenic drug that can be chronically administered for cancer therapy or metastasis prevention and first reaches the liver, making it especially efficient in preventing the development of liver metastasis in mice.

TL;DR: Monomethoxy polyethylene glycol-poly lactic acid micelles are developed as a drug nanocarrier, and the mechanism of uptake across intestinal cells is studied, finding that mPEG-PLA nanoparticle endocytosis is mediated by clathrin in an energy-dependent manner, and that the low-density lipoprotein receptor is involved.