F
Florian Holtbernd
Researcher at RWTH Aachen University
Publications - 21
Citations - 488
Florian Holtbernd is an academic researcher from RWTH Aachen University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 7, co-authored 17 publications receiving 337 citations. Previous affiliations of Florian Holtbernd include The Feinstein Institute for Medical Research & Forschungszentrum Jülich.
Papers
More filters
Journal ArticleDOI
Abnormal metabolic network activity in REM sleep behavior disorder
Florian Holtbernd,Jean-François Gagnon,Ronald B. Postuma,Yilong Ma,Chris C. Tang,Andrew Feigin,Vijay Dhawan,Mélanie Vendette,Jean-Paul Soucy,David Eidelberg,Jacques Montplaisir +10 more
TL;DR: Latent network abnormalities in subjects with idiopathic RBD are associated with a greater likelihood of subsequent phenoconversion to a progressive neurodegenerative syndrome.
Journal ArticleDOI
Brain imaging findings in idiopathic REM sleep behavior disorder (RBD) – A systematic review on potential biomarkers for neurodegeneration
Julia Heller,Nikolina Brcina,Imis Dogan,Florian Holtbernd,Sandro Romanzetti,Jörg B. Schulz,Johannes Schiefer,Kathrin Reetz +7 more
TL;DR: Recent advances in brain imaging in RBD are summarized and recommendations for the application of currently available structural and functional neuroimaging modalities to monitor disease progression and risk of subsequent phenoconversion are provided.
Journal ArticleDOI
Dopaminergic correlates of metabolic network activity in Parkinson's disease
Florian Holtbernd,Yilong Ma,Schichun Peng,Frank L. Schwartz,Lars Timmermann,Lutz W. Kracht,Gereon R. Fink,Gereon R. Fink,Chris C. Tang,David Eidelberg,Carsten Eggers +10 more
TL;DR: Overall, the data indicate that PDRP and PDCP expression correlates significantly with PET indices of presynaptic dopaminergic functioning obtained in the same individuals, suggesting that in PD patients, individual differences in network activity cannot be explained solely by nigrostriatal dopamine loss.
Journal ArticleDOI
Progression characteristics of the European Friedreich's Ataxia Consortium for Translational Studies (EFACTS): a 4-year cohort study.
Kathrin Reetz,Imis Dogan,Ralf-Dieter Hilgers,Paola Giunti,Michael H Parkinson,Caterina Mariotti,Lorenzo Nanetti,Alexandra Durr,Claire Ewenczyk,Sylvia Boesch,Wolfgang Nachbauer,Thomas Klopstock,Thomas Klopstock,Claudia Stendel,Claudia Stendel,Francisco Javier Rodríguez de Rivera Garrido,Christian Rummey,Ludger Schöls,Ludger Schöls,Stefanie N. Hayer,Thomas Klockgether,Thomas Klockgether,Ilaria Giordano,Claire Didszun,Myriam Rai,Massimo Pandolfo,Jörg B. Schulz,Robyn Labrum,Gilbert Thomas-Black,Katarina Manso,Nita Solanky,Cinzia Gellera,Alessia Mongelli,Anna Castaldo,M. Fichera,Francesc Palau,Mar O'Callaghan,Marie Biet,Marie Lorraine Monin,Andreas Eigentler,Elisabetta Indelicato,Matthias Amprosi,Florentine Radelfahr,Almut Turid Bischoff,Florian Holtbernd,Nikolina Brcina,Christian Hohenfeld,Georgios Koutsis,Marianthi Breza,Enrico Bertini,Gessica Vasco +50 more
TL;DR: The European Friedreich's Ataxia Consortium for Translational Studies (EFACTS) as discussed by the authors investigated the natural history and progression characteristics of the disease and identified patient groups with differential progression rates based on longitudinal 4-year data to inform upcoming clinical trials.
Journal ArticleDOI
Functional brain networks in movement disorders: recent advances.
TL;DR: The promising findings from recent studies may help to establish new and reliable biomarkers to monitor disease progression and treatment effects in future clinical trials.