C
Claire Ewenczyk
Researcher at University of Paris
Publications - 50
Citations - 1538
Claire Ewenczyk is an academic researcher from University of Paris. The author has contributed to research in topics: Ataxia & Medicine. The author has an hindex of 17, co-authored 39 publications receiving 999 citations. Previous affiliations of Claire Ewenczyk include French Institute of Health and Medical Research & ICM Partners.
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Journal ArticleDOI
The coeruleus/subcoeruleus complex in rapid eye movement sleep behaviour disorders in Parkinson's disease.
Daniel García-Lorenzo,Clarisse Longo dos Santos,Claire Ewenczyk,Smaranda Leu-Semenescu,Cecile Gallea,Graziella Quattrocchi,Patricia Pita Lobo,Cyril Poupon,Habib Benali,Habib Benali,Isabelle Arnulf,Marie Vidailhet,Stéphane Lehéricy +12 more
TL;DR: The results confirmed that this complex is affected in Parkinson’s disease and showed a gradual relationship between damage to this structure, presumably the locus subcoeruleus, and abnormal muscle tone during rapid eye movement sleep, which is the cardinal marker of rapidEye movement sleep behaviour disorder.
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Progression characteristics of the European Friedreich’s Ataxia Consortium for Translational Studies (EFACTS): a 2 year cohort study
Kathrin Reetz,Imis Dogan,Ralf-Dieter Hilgers,Paola Giunti,Caterina Mariotti,Alexandra Durr,Sylvia Boesch,Thomas Klopstock,Thomas Klopstock,Francisco Javier Rodriguez de Rivera,Ludger Schöls,Ludger Schöls,Thomas Klockgether,Thomas Klockgether,Katrin Bürk,Myriam Rai,Massimo Pandolfo,Jörg B. Schulz,Wolfgang Nachbauer,Andreas Eigentler,Chantal Depondt,Sandra Benaich,Perrine Charles,Claire Ewenczyk,Marie-Lorraine Monin,Manuel Dafotakis,Kathrin Fedosov,Claire Didszun,Ummehan Ermis,Ilaria Giordano,Dagmar Timmann,Ivan Karin,Christiane Neuhofer,Claudia Stendel,Jennifer Müller vom Hagen,Julia Wolf,Marta Panzeri,Lorenzo Nanetti,Anna Castaldo,Javier Arpa,Irene Sanz-Gallego,Michael H Parkinson,Mary G. Sweeney +42 more
TL;DR: The results show that SARA is a suitable clinical rating scale to detect deterioration of ataxia symptoms over time; ADL is an appropriate measure to monitor changes in daily self-care activities; and younger age at disease onset is a major predictor for faster disease progression.
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A panel study on patients with dominant cerebellar ataxia highlights the frequency of channelopathies.
Marie Coutelier,Giulia Coarelli,Marie-Lorraine Monin,Juliette Konop,Claire-Sophie Davoine,Christelle Tesson,Rémi Valter,Mathieu Anheim,Anthony Behin,Giovanni Castelnovo,Perrine Charles,Albert David,Claire Ewenczyk,Mélanie Fradin,Cyril Goizet,Didier Hannequin,Pierre Labauge,Florence Riant,Pierre Sarda,Yves Sznajer,François Tison,Urielle Ullmann,Lionel Van Maldergem,Lionel Van Maldergem,Fanny Mochel,Alexis Brice,Giovanni Stevanin,Alexandra Durr +27 more
TL;DR: Important genetic variations are identified in up to 15% of cases after exclusion of polyglutamine expansion spinocerebellar ataxias, and CACNA1A and SPG7 are confirmed as major ataxia genes, to delineate firm genotype-phenotype correlations that are important for genetic counselling and of possible prognostic value.
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Efficacy of Exome-Targeted Capture Sequencing to Detect Mutations in Known Cerebellar Ataxia Genes.
Marie Coutelier,Monia B. Hammer,Giovanni Stevanin,Marie-Lorraine Monin,Claire-Sophie Davoine,Fanny Mochel,Pierre Labauge,Claire Ewenczyk,Jinhui Ding,J. Raphael Gibbs,Didier Hannequin,Judith Melki,Annick Toutain,Vincent Laugel,Sylvie Forlani,Perrine Charles,Emmanuel Broussolle,Emmanuel Broussolle,Stéphane Thobois,Stéphane Thobois,Alexandra Afenjar,Mathieu Anheim,Patrick Calvas,Giovanni Castelnovo,Thomas De Broucker,Marie Vidailhet,Antoine Moulignier,Robert T. Ghnassia,Chantal M. E. Tallaksen,Cyril Mignot,Cyril Goizet,Isabelle Le Ber,Elisabeth Ollagnon-Roman,Jean Pouget,Alexis Brice,Andrew B. Singleton,Alexandra Durr +36 more
TL;DR: To assess the efficacy of exome-targeted capture sequencing to detect mutations in genes broadly linked to CA in a large cohort of undiagnosed patients and to investigate their prevalence, exome capture followed by targeted analysis is performed.
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PPNa-DBS for gait and balance disorders in Parkinson’s disease: a double-blind, randomised study
Marie-Laure Welter,Adèle Demain,Claire Ewenczyk,Virginie Czernecki,Brian Lau,Amine El Helou,Hayat Belaid,Jérôme Yelnik,Chantal François,Eric Bardinet,Carine Karachi,David Grabli +11 more
TL;DR: It is suggested that PPNa-DBS could improve gait and balance disorders in well-selected PD patients, however, this treatment may be riskier than others DBS surgeries in these patients with an advanced form of PD.