F
Fotios Drenos
Researcher at Brunel University London
Publications - 119
Citations - 8978
Fotios Drenos is an academic researcher from Brunel University London. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 40, co-authored 110 publications receiving 7662 citations. Previous affiliations of Fotios Drenos include University College London & University of Newcastle.
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Journal ArticleDOI
Correction: Clinical utility of a coronary heart disease risk prediction gene score in UK healthy middle aged men and in the Pakistani population PLoS ONE 10 (7). doi: 10.1371/journal.pone.0130754
Journal ArticleDOI
The use of genetic information in the prediction of Type 2 diabetes.
Fotios Drenos,Fotios Drenos +1 more
TL;DR: Genetics could soon be able to be used, not to quantify risk, but to inform clinicians on those requiring earlier observation, as well as in reclassification but are too modest for clinical use.
Posted ContentDOI
Increased adiposity is protective for breast and prostate cancer: a Mendelian randomisation study using up to 132,413 breast cancer cases and 85,907 prostate cancer cases
Hasnat A Amin,Pimpika Kaewsri,Andrianos M. Yiorkas,Heather Cooke,Alexandra I. F. Blakemore,Fotios Drenos +5 more
TL;DR: Increasing adiposity is causally protective for breast and prostate cancer and the effects in prostate cancer may, at least partly, be due to the safe storage of chemicals in adipose cells.
Posted ContentDOI
Metabolic signatures of birth weight in 18 288 adolescents and adults
Peter Würtz,Qin Wang,Qin Wang,Marjo Niironen,Marjo Niironen,Tuulia Tynkkynen,Tuulia Tynkkynen,Mika Tiainen,Mika Tiainen,Fotios Drenos,Antti J. Kangas,Pasi Soininen,Pasi Soininen,Michael R. Skilton,Kauko Heikkilä,Anneli Pouta,Anneli Pouta,Mika Kähönen,Terho Lehtimäki,Richard J. Rose,Eero Kajantie,Eero Kajantie,Eero Kajantie,Markus Perola,Markus Perola,Jaakko Kaprio,Jaakko Kaprio,Johan G. Eriksson,Olli T. Raitakari,Olli T. Raitakari,Debbie A Lawlor,George Davey Smith,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Mika Ala-Korpela,Kirsi Auro,Kirsi Auro +36 more
TL;DR: The findings indicate that fetal growth, as assessed by birth weight, only has minor effects on the adult metabolic risk profile in general population settings, and that birth weight is only a weak indicator of metabolic risk in adulthood.
Posted ContentDOI
Alcohol causes an increased risk of head and neck but not breast cancer in individuals from the UK Biobank study: A Mendelian randomisation analysis
TL;DR: It is found that increasing alcohol consumption, especially above the recommended level, was causal to head and neck cancers but not breast cancer, and the suggested threshold of 14 units/week appears suitable to manage the risk of cancer due to alcohol.