F
Francesc Balaguer
Researcher at University of Barcelona
Publications - 241
Citations - 8187
Francesc Balaguer is an academic researcher from University of Barcelona. The author has contributed to research in topics: Colorectal cancer & Cancer. The author has an hindex of 42, co-authored 194 publications receiving 6594 citations. Previous affiliations of Francesc Balaguer include Baylor University & Baylor University Medical Center.
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Journal ArticleDOI
Integrated Analysis of Germline and Tumor DNA Identifies New Candidate Genes Involved in Familial Colorectal Cancer
Marcos Díaz-Gay,Sebastià Franch-Expósito,Coral Arnau-Collell,Solip Park,Fran Supek,Jenifer Muñoz,Laia Bonjoch,Anna Gratacós-Mulleras,Paula A. Sánchez-Rojas,Clara Esteban-Jurado,Teresa Ocaña,Miriam Cuatrecasas,Maria Vila-Casadesús,Juan José Lozano,Genís Parra,Steve Laurie,Sergi Beltran,Antoni Castells,Luis Bujanda,Joaquín Cubiella,Francesc Balaguer,Sergi Castellví-Bel +21 more
TL;DR: BRCA2, BLM, ERCC2, RECQL, REV3L and RIF1 were among the most promising candidate genes for germline CRC predisposition, and the identification of new candidate genes involved in familial CRC could be achieved by the integrated analysis.
Journal ArticleDOI
Germline and Somatic Whole-Exome Sequencing Identifies New Candidate Genes Involved in Familial Predisposition to Serrated Polyposis Syndrome.
Yasmin Soares de Lima,Coral Arnau-Collell,Marcos Díaz-Gay,Laia Bonjoch,Sebastià Franch-Expósito,Jenifer Muñoz,Leticia Moreira,Teresa Ocaña,Miriam Cuatrecasas,Cristina Herrera-Pariente,Sabela Carballal,Lorena Moreno,Aránzazu Díaz de Bustamante,Antoni Castells,Luis Bujanda,Joaquín Cubiella,Daniel Rodríguez-Alcalde,Francesc Balaguer,Sergi Castellví-Bel +18 more
TL;DR: In this article, the authors identify new candidate genes involved in the germline predisposition to serrated polyposis syndrome (SPS) and colorectal cancer (CRC).
Journal ArticleDOI
Multiple Sporadic Colorectal Cancers Display a Unique Methylation Phenotype
Victoria Gonzalo,Juan José Lozano,Virginia Alonso-Espinaco,Leticia Moreira,Jenifer Muñoz,Maria Pellise,Sergi Castellví-Bel,Xavier Bessa,Montserrat Andreu,Rosa M. Xicola,Xavier Llor,Clara Ruiz-Ponte,Angel Carracedo,Rodrigo Jover,Antoni Castells,Francesc Balaguer +15 more
TL;DR: Functional analysis of hypermethylated genes found in multiple tumors showed enrichment of genes involved in different tumorigenic functions, which may be important to unravel the underlying mechanism of tumor multiplicity.
Journal ArticleDOI
Colorectal cancer after negative colonoscopy in fecal immunochemical test-positive participants from a colorectal cancer screening program.
Liseth Rivero-Sánchez,Jaume Grau,Josep M. Augé,Lorena Moreno,Angels Pozo,Anna Serradesanferm,Mireia Díaz,Sabela Carballal,Ariadna Sánchez,Leticia Moreira,Francesc Balaguer,Maria Pellise,Antoni Castells +12 more
TL;DR: The very low incidence of post-colonoscopy colorectal cancer (PCCRC) and characteristics of PCCRC observed in participants from the first round of a CRC screening program reinforce the concept that, although a positive FIT preselects high risk individuals, a high quality colonoscopy is the paramount factor in preventing P CCRC.
Journal ArticleDOI
Colorectal cancer genetic variants are also associated with serrated polyposis syndrome susceptibility.
Coral Arnau-Collell,Yasmin Soares de Lima,Marcos Díaz-Gay,Jenifer Muñoz,Sabela Carballal,Laia Bonjoch,Leticia Moreira,Juan José Lozano,Teresa Ocaña,Miriam Cuatrecasas,Aránzazu Díaz de Bustamante,Antoni Castells,Gabriel Capellá,Luis Bujanda,Joaquín Cubiella,Daniel Rodríguez-Alcalde,Francesc Balaguer,Clara Ruiz-Ponte,Laura Valle,Victor Moreno,Sergi Castellví-Bel +20 more
TL;DR: Genetic variants for CRC risk are also involved in SPS susceptibility, being the most relevant ones rs4779584-GREM1, rs16892766-EIF3H and rs3217810-CCND2.