F
Francesco Latrofa
Researcher at University of Pisa
Publications - 82
Citations - 2935
Francesco Latrofa is an academic researcher from University of Pisa. The author has contributed to research in topics: Thyroid & Thyroglobulin. The author has an hindex of 26, co-authored 67 publications receiving 2253 citations. Previous affiliations of Francesco Latrofa include World Health Organization & University of California, Los Angeles.
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Journal ArticleDOI
Disappearance of humoral thyroid autoimmunity after complete removal of thyroid antigens.
Luca Chiovato,Francesco Latrofa,Lewis E. Braverman,Furio Pacini,Marco Capezzone,Lucio Masserini,Lucia Grasso,Aldo Pinchera +7 more
TL;DR: A large group of patients with differentiated thyroid carcinoma who had serum thyroid peroxidase, thyroglobulin, or TSH-receptor antibodies due to coexistent thyroid autoimmune disease were studied, finding gradual disappearance of antibodies gradually disappeared in most patients.
Journal ArticleDOI
Subacute Thyroiditis After Sars-COV-2 Infection.
Alessandro Brancatella,Debora Ricci,Nicola Viola,Daniele Sgrò,Ferruccio Santini,Francesco Latrofa +5 more
TL;DR: The first case of SAT related to SARS-CoV-2 infection is reported and clinicians are alerted to additional and unreported clinical manifestations associated with COVID-19.
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The thyrotropin receptor autoantigen in Graves disease is the culprit as well as the victim
Chun-Rong Chen,Pavel N. Pichurin,Yuji Nagayama,Francesco Latrofa,Basil Rapoport,Sandra M. McLachlan +5 more
TL;DR: Goiter and hyperthyroidism occur to a much greater extent when the adenovirus expresses the free A subunit as opposed to a genetically modified TSHR that cleaves minimally into subunits, and new insight is provided into the etiology of Graves disease.
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Detection of SARS-COV-2 receptor ACE-2 mRNA in thyroid cells: a clue for COVID-19-related subacute thyroiditis
Mario Rotondi,Francesca Coperchini,Gianluca Ricci,Marco Denegri,Laura Croce,Samuel Tata Ngnitejeu,Laura Villani,Flavia Magri,Francesco Latrofa,Luca Chiovato +9 more
TL;DR: The results of the present study demonstrate that the mRNA encoding for the ACE-2 receptor is expressed in thyroid follicular cells, making them a potential target for SARS-COV-2 entry.
Journal ArticleDOI
Thyroid-stimulating autoantibodies in Graves disease preferentially recognize the free A subunit, not the thyrotropin holoreceptor
Gregorio D. Chazenbalk,Pavel N. Pichurin,Chun-Rong Chen,Francesco Latrofa,Alan P. Johnstone,Sandra M. McLachlan,Basil Rapoport +6 more
TL;DR: Evidence supports the concept that A subunit shedding either initiates or amplifies the autoimmune response to the TSHR, thereby causing Graves disease in genetically susceptible individuals.