F
Francisco E. Martín-Cano
Researcher at University of Extremadura
Publications - 46
Citations - 499
Francisco E. Martín-Cano is an academic researcher from University of Extremadura. The author has contributed to research in topics: Sperm & Medicine. The author has an hindex of 12, co-authored 36 publications receiving 328 citations.
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Journal ArticleDOI
Dynamic interaction of SARAF with STIM1 and orai1 to modulate store-operated calcium entry
Letizia Albarran,Jose J. Lopez,Nidhal Ben Amor,Francisco E. Martín-Cano,Alejandro Berna-Erro,Tarik Smani,Ginés M. Salido,Juan A. Rosado +7 more
TL;DR: Evidence for the dynamic interaction between the SOCE-associated regulatory factor (SARAF), STIM1 and Orai1 is presented to suggest that SARAF exerts an initial positive role in the activation of SOCE followed by the facilitation of SCDI of ORAi1.
Journal ArticleDOI
Melatonin, a Potential Therapeutic Agent for Smooth Muscle-Related Pathological Conditions and Aging
Maria J. Pozo,Pedro J. Gomez-Pinilla,Cristina Camello-Almaraz,Francisco E. Martín-Cano,Patricia Pascua,M. A. Rol,Darío Acuña-Castroviejo,Pedro J. Camello +7 more
TL;DR: Melatonin is a promising candidate for future research of agents that modulate smooth muscle motility and reverses bladder damage following ischemia/reperfusion.
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Melatonin induces neural SOD2 expression independent of the NF-kappaB pathway and improves the mitochondrial population and function in old mice
Marina García-Macia,Ignacio Vega-Naredo,David de Gonzalo-Calvo,Susana Rodríguez-González,Pedro J. Camello,Cristina Camello-Almaraz,Francisco E. Martín-Cano,María Josefa Rodríguez-Colunga,Maria J. Pozo,Ana Coto-Montes +9 more
TL;DR: Melatonin’s beneficial effects on brain aging are linked to the increase in mitochondrial membrane potential and SOD2 expression, which probably reduces the mitochondrial contribution to the oxidative stress imbalance.
Journal ArticleDOI
Proteomic profiling of stallion spermatozoa suggests changes in sperm metabolism and compromised redox regulation after cryopreservation
Francisco E. Martín-Cano,Gemma Gaitskell-Phillips,José M. Ortiz-Rodríguez,Antonio Silva-Rodríguez,Angel Carlos Roman,Patricia Rojo-Domínguez,Esmeralda Alonso-Rodríguez,Jose A. Tapia,María Concepción Robles Gil,Cristina Ortega-Ferrusola,Fernando J. Peña +10 more
TL;DR: It is reported that cryopreservation impacts numerous proteins involved in metabolism regulation (mainly mitochondria involved in the TCA cycle, and oxidative phosphorylation) and also affect proteins with oxidoreductase activity.
Journal ArticleDOI
Mass spectrometry reveals distinct proteomic profiles in high- and low-quality stallion spermatozoa.
Roisin Ann Griffin,Aleona Swegen,Aleona Swegen,Mark Baker,Robert John Aitken,David A. Skerrett-Byrne,Antonio Silva Rodríguez,Francisco E. Martín-Cano,Brett Nixon,Fernando J. Peña,Maryse Delehedde,Nicolas Sergeant,Zamira Gibb +12 more
TL;DR: In conclusion, the proteomic profiles of high- and low-quality stallion spermatozoa differ substantially, and proteins such as AKAP4 and HK1 could serve as biomarkers of ejaculate quality.