F
Francisco Martínez
Researcher at Instituto Politécnico Nacional
Publications - 225
Citations - 5353
Francisco Martínez is an academic researcher from Instituto Politécnico Nacional. The author has contributed to research in topics: Medicine & Gene. The author has an hindex of 34, co-authored 188 publications receiving 4710 citations. Previous affiliations of Francisco Martínez include Valparaiso University & University of Paris-Sud.
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Journal ArticleDOI
A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation.
Patrick S. Tarpey,Raffaella Smith,Erin Pleasance,Annabel Whibley,Sarah Edkins,Claire Hardy,Sarah O’Meara,Calli Latimer,Ed Dicks,Andrew Menzies,Phil Stephens,Matt Blow,Christopher Greenman,Yali Xue,Chris Tyler-Smith,Deborah J. Thompson,Kristian Gray,Jenny Andrews,Syd Barthorpe,Gemma Buck,Jennifer Cole,Rebecca Dunmore,David T. Jones,Mark Maddison,Tatiana Mironenko,Rachel Turner,Kelly Turrell,Jennifer Varian,Sofie West,Sara Widaa,Paul Wray,Jon W. Teague,Adam Butler,Andrew M. Jenkinson,Mingming Jia,David S. Richardson,Rebecca Shepherd,Richard Wooster,M Isabel Tejada,Francisco Martínez,Gemma L. Carvill,Rene Goliath,Arjan P.M. de Brouwer,Hans van Bokhoven,Hilde Van Esch,Jamel Chelly,Martine Raynaud,Hans-Hilger Ropers,Fatima Abidi,Anand Srivastava,James J. Cox,Ying Luo,Uma Mallya,Jenny Moon,Josef Parnau,Shehla Mohammed,John Tolmie,Cheryl Shoubridge,Mark A. Corbett,Alison Gardner,Eric Haan,Sinitdhorn Rujirabanjerd,Marie Shaw,Lucianne Vandeleur,Tod Fullston,Douglas F. Easton,Jackie Boyle,Michael Partington,Anna Hackett,Michael Field,Cindy Skinner,Roger E. Stevenson,Martin Bobrow,Gillian Turner,Charles E. Schwartz,Jozef Gecz,Jozef Gecz,F. Lucy Raymond,P. Andrew Futreal,Michael R. Stratton +79 more
TL;DR: The coding exons of the X chromosome in 208 families with X-linked mental retardation (XLMR) are sequenced, the largest direct screen for constitutional disease-causing mutations thus far reported.
Journal ArticleDOI
Molecular biology of neuroblastoma
TL;DR: Recent advances in the understanding of the biology of neuroblastoma are focused on one of the first examples for the use of tumoral genetic markers as a tool for defining tumour behaviour and to aid clinical staging.
Journal ArticleDOI
Polscope analysis of meiotic spindle changes in living metaphase II human oocytes during the freezing and thawing procedures
Laura Rienzi,Francisco Martínez,Filippo Ubaldi,Maria Giulia Minasi,Marcello Iacobelli,Jan Tesarik,Ermanno Greco +6 more
TL;DR: The current techniques of oocyte freezing and thawing inevitably cause meiotic spindle destruction, and all spindles observed in thawed oocytes result from post-thaw reconstruction.
Journal ArticleDOI
Severe Infections after Unrelated Donor Allogeneic Hematopoietic Stem Cell Transplantation in Adults: Comparison of Cord Blood Transplantation with Peripheral Blood and Bone Marrow Transplantation
Rocío Parody,Rodrigo Martino,Montserrat Rovira,Lourdes Vázquez,María José Vázquez,Rafael de la Cámara,Cristina Blazquez,Francesc Fernández-Avilés,Enric Carreras,Miguel Salavert,Isidro Jarque,Carmen Martín,Francisco Martínez,Javier María García López,Antoni Torres,Jorge Sierra,Guilllermo F. Sanz +16 more
TL;DR: The results confirm the relevance of severe infectious complications as source of severe morbidity and NRM after volunteer unrelated donor hematopoietic stem cell transplantation in adults, but suggest that CBT recipients have a similar risk of dying from an infection if an accurate selection of a cord blood unit is done.
Journal ArticleDOI
Relationship between meiotic spindle location with regard to the polar body position and oocyte developmental potential after ICSI
Laura Rienzi,Filippo Ubaldi,Francisco Martínez,Marcello Iacobelli,Maria Giulia Minasi,Susanna Ferrero,Jan Tesarik,Ermanno Greco +7 more
TL;DR: High degrees of misalignment between the meiotic spindle and the first PB predict an increased risk of fertilization abnormalities, and facilitate the selection of oocytes for ICSI in situations when the creation of supernumerary embryos is to be avoided.