G
Galina E. Pozmogova
Researcher at Federal Biomedical Agency
Publications - 72
Citations - 919
Galina E. Pozmogova is an academic researcher from Federal Biomedical Agency. The author has contributed to research in topics: Oligonucleotide & DNA. The author has an hindex of 16, co-authored 72 publications receiving 745 citations. Previous affiliations of Galina E. Pozmogova include Russian Academy & Peninsular Malaysia.
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Journal ArticleDOI
DNA modification of live cell surface
TL;DR: A novel approach for the attachment of DNA fragments to the surface of live cells allows rapid and simple DNA multicoding of the cell surface and opens new opportunities in manipulating with cell–cell interactions.
Journal ArticleDOI
The expanding repertoire of G4 DNA structures
Anna M. Varizhuk,Dmitry S. Ischenko,Vladimir B. Tsvetkov,Roman A. Novikov,Nikolay A. Kulemin,Dmitry N. Kaluzhny,Maria Vlasenok,Vladimir Naumov,Igor P. Smirnov,Galina E. Pozmogova +9 more
TL;DR: It is suggested that, similar to classical G4s, imperfect G 4s could be considered as potential regulatory elements, pathology biomarkers and therapeutic targets, reflecting the enhanced sequential diversity of these motifs.
Journal ArticleDOI
Conformation and thermostability of oligonucleotide d(GGTTGGTGTGGTTGG) containing thiophosphoryl internucleotide bonds at different positions.
M. A. Zaitseva,Dmitry N. Kaluzhny,Anna K. Shchyolkina,Olga F. Borisova,Igor P. Smirnov,Galina E. Pozmogova +5 more
TL;DR: According to the thrombin time test, the aptamer with thio-modifications in both TT loops (LL11) exhibits the same antithrombin efficiency as the original TBA, and shows better stability against DNA nuclease compared to that of TBA.
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Synthesis, characterization and in vitro activity of thrombin-binding DNA aptamers with triazole internucleotide linkages.
Anna M. Varizhuk,Vladimir B. Tsvetkov,Olga N. Tatarinova,Dmitry N. Kaluzhny,V. L. Florentiev,Edward N. Timofeev,Anna K. Shchyolkina,Olga F. Borisova,Igor P. Smirnov,S. L. Grokhovsky,Anton V. Aseychev,Galina E. Pozmogova +11 more
TL;DR: Due to their relatively high activity and the increased resistance to nuclease digestion imparted by the triazole internucleotide linkages, the novel aptamers are a promising alternative to known DNA-based anticoagulant agents.
Journal ArticleDOI
Synthesis of triazole-linked oligonucleotides with high affinity to DNA complements and an analysis of their compatibility with biosystems.
Anna M. Varizhuk,Anna M. Varizhuk,Dmitry N. Kaluzhny,Roman A. Novikov,Alexandr O. Chizhov,Igor P. Smirnov,A. N. Chuvilin,Olga N. Tatarinova,Gleb Y. Fisunov,Galina E. Pozmogova,V. L. Florentiev +10 more
TL;DR: These new oligonucleotide analogues with triazole internucleotide linkages with remote from the 3'-terminus were synthesized and their hybridization properties were studied, suggesting that they are among the most promising Triazole DNA mimics characterized to date.