G
Gan-Xin Yan
Researcher at Lankenau Institute for Medical Research
Publications - 115
Citations - 10902
Gan-Xin Yan is an academic researcher from Lankenau Institute for Medical Research. The author has contributed to research in topics: QT interval & Repolarization. The author has an hindex of 42, co-authored 105 publications receiving 10110 citations. Previous affiliations of Gan-Xin Yan include Case Western Reserve University & Xi'an Jiaotong University.
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Journal ArticleDOI
The funny current (If): is it a novel antiarrhythmic target to treat atrial fibrillation?
TL;DR: The Funny Current (If): Is it a Novel Antiarrhythmic Target to Treat Atrial Fibrillation?
Journal ArticleDOI
Inhibitory Effect of Vascular Endothelial Growth Factor on the Slowly Activating Delayed Rectifier Potassium Current in Guinea Pig Ventricular Myocytes
TL;DR: A promising therapeutic potential is indicated in prevention of ventricular tachyarrhythmias under conditions of high sympathetic activity and ischemia through a phosphatidylinositol 3‐kinase–mediated signaling pathway, leading to AP prolongation.
Journal ArticleDOI
Genotype-Phenotype Correlation of SCN5A Genotype in Patients With Brugada Syndrome and Arrhythmic Events: Insights From the SABRUS in 392 Probands.
Anat Milman,Anat Milman,Elijah R. Behr,Belinda Gray,David C Johnson,Antoine Andorin,Aviram Hochstadt,Aviram Hochstadt,Jean-Baptiste Gourraud,Shingo Maeda,Yoshihide Takahashi,Jimmy Jm Juang,Sung Hwan Kim,T Kamakura,Takeshi Aiba,Pieter G. Postema,Yuka Mizusawa,Isabelle Denjoy,Carla Giustetto,Giulio Conte,Zhengrong Huang,Georgia Sarquella-Brugada,Andrea Mazzanti,Camilla H Jespersen,Camilla H Jespersen,Elena Arbelo,Ramon Brugada,Leonardo Calò,Domenico Corrado,Ruben Casado-Arroyo,Giuseppe Allocca,Masahiko Takagi,P. Delise,Josep Brugada,Jacob Tfelt-Hansen,Jacob Tfelt-Hansen,Silvia G Priori,Christian Veltmann,Gan-Xin Yan,Pedro Brugada,Fiorenzo Gaita,Antoine Leenhardt,Arthur A.M. Wilde,Kengo Kusano,Gi-Byoung Nam,Kenzo Hirao,Vincent Probst,Bernard Belhassen +47 more
TL;DR: In this article, Brugada syndrome (BrS) is associated with mutations in the cardiac sodium channel gene, SCN5A, and genetic studies of patients with BrS with arrhythmic events are limited.
Journal ArticleDOI
Differentiating electrophysiological effects and cardiac safety of drugs based on in vitro electrocardiogram: A blinded validation
Tengxian Liu,Martin Traebert,Haisong Ju,Willi Suter,Donglin Guo,Peter R. Hoffmann,Peter R. Kowey,Gan-Xin Yan +7 more
Journal Article
Abstract 10380: The Ashman Phenomenon in Patients With Atrial fibrillation Treated With an IKr Blocker, Dofetilide
TL;DR: The Ashman phenomenon is aberrant ventricular conduction that often occurs during a short-long-short R-R interval in patients with atrial fibrillation.