G
Gary L. Pattee
Researcher at University of Nebraska Medical Center
Publications - 69
Citations - 1833
Gary L. Pattee is an academic researcher from University of Nebraska Medical Center. The author has contributed to research in topics: Amyotrophic lateral sclerosis & Medicine. The author has an hindex of 20, co-authored 54 publications receiving 1261 citations. Previous affiliations of Gary L. Pattee include Nebraska Medical Center.
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Journal ArticleDOI
Trial of Sodium Phenylbutyrate–Taurursodiol for Amyotrophic Lateral Sclerosis
Sabrina Paganoni,Eric A. Macklin,Suzanne Hendrix,James D. Berry,Michael A. Elliott,Samuel Maiser,Chafic Karam,James B. Caress,Margaret A. Owegi,Adam Quick,James Wymer,Stephen A. Goutman,Daragh Heitzman,Terry Heiman-Patterson,Carlayne E. Jackson,Colin Quinn,Jeffrey D. Rothstein,Edward J. Kasarskis,Jonathan S. Katz,Liberty Jenkins,Shafeeq Ladha,Timothy M. Miller,Stephen N. Scelsa,Tuan Vu,Christina Fournier,Jonathan D. Glass,Kristin M. Johnson,Andrea Swenson,Namita Goyal,Gary L. Pattee,Patricia L. Andres,Suma Babu,Marianne Chase,Derek Dagostino,Samuel P. Dickson,Noel Ellison,Meghan Hall,Kent Allen Hendrix,Gale Kittle,Michelle McGovern,Joseph Ostrow,Lindsay Pothier,Rebecca Randall,Jeremy M. Shefner,Alexander Sherman,Eric Tustison,Prasha Vigneswaran,Jason Walker,Hong Yu,James Chan,Janet Wittes,Joshua D. Cohen,Justin Klee,Kent L. Leslie,Rudolph E. Tanzi,Walter Gilbert,Patrick D. Yeramian,David A. Schoenfeld,Merit Cudkowicz +58 more
TL;DR: Sodium phenylbutyrate-taurursodiol resulted in slower functional decline than placebo as measured by the ALSFRS-R score over a period of 24 weeks, and was found to reduce neuronal death in experimental models.
Journal ArticleDOI
Bulbar and speech motor assessment in ALS: Challenges and future directions
Jordan R. Green,Yana Yunusova,Mili S. Kuruvilla,Jun Wang,Gary L. Pattee,Lori Synhorst,Lorne Zinman,James D. Berry +7 more
TL;DR: In this paper, the authors considered objective measures of speech motor function, which show promise for forming the basis of a comprehensive, quantitative bulbar motor assessment in ALS, based on the assessment of four speech subsystems: respiratory, phonatory, articulatory, and resonatory.
Journal ArticleDOI
Communication Effectiveness of Individuals with Amyotrophic Lateral Sclerosis.
TL;DR: The results of this study revealed that perceptions of communication effectiveness for speakers with ALS were quite similar for the speakers and their frequent listeners across 10 different social situations.
Journal ArticleDOI
Kinematics of disease progression in bulbar ALS.
Yana Yunusova,Jordan R. Green,Mary J. Lindstrom,Laura J. Ball,Gary L. Pattee,Lorne Zinman,Lorne Zinman +6 more
TL;DR: Investigating the deterioration of lip and jaw movements during speech longitudinally in three individuals diagnosed with bulbar amyotrophic lateral sclerosis revealed several changes inlip and jaw movement that coincided with ALS progression.
Journal ArticleDOI
A protocol for identification of early bulbar signs in amyotrophic lateral sclerosis
TL;DR: The data identified that the strongest early predictors of bulbar speech dysfunction include altered voice quality (laryngeal control), speaking rate, and communication effectiveness.