Gary R. Hunnicutt

TL;DR: It is shown that Sept4 proteins play distinct but evolutionarily conserved functions in different cellular compartments, consistent with a role of the proapoptotic Sept4 protein ARTS in promoting caspase-mediated removal of cytoplasm via inhibition of XIAP.

TL;DR: Data indicated that sperm membranes possess distinct raft subdomains, and that caveolin-1 localized to regions appropriate for involvement with acrosomal biogenesis and exocytosis, as well as signaling pathways regulating such processes as capacitation and flagellar motility.

TL;DR: It is posited that basigin may not diffuse freely until after the annulus arrives at the midpiece-principal piece junction to restrict lateral movement, the strongest evidence to date of a mammalian septin structure establishing a membrane diffusion barrier.

TL;DR: Evidence is reported that a common mechanism may be used to change the localization pattern of other sperm surface molecules, shown to become localized to either the posterior or the anterior head membrane domains on sperm at the same time fertilin became localized to the posterior head.

TL;DR: Assessing changes in G(M1) distribution in response to progesterone-induced AE shows that these patterns reflect the response of murine sperm populations to capacitating stimuli, suggesting that G( M1) localization can be used as a diagnostic tool for evaluating sperm response to stimuli for capacitation and/or AE.