G
Geert Leroux-Roels
Researcher at Ghent University Hospital
Publications - 82
Citations - 2866
Geert Leroux-Roels is an academic researcher from Ghent University Hospital. The author has contributed to research in topics: Vaccination & Reactogenicity. The author has an hindex of 29, co-authored 82 publications receiving 2389 citations.
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Journal ArticleDOI
Hepatitis A booster vaccination: is there a need?
Pierre Van Damme,J. E. Banatvala,O Fay,S Iwarson,Brian J. McMahon,K. van Herck,Daniel Shouval,Paolo Bonanni,Bradley A. Connor,G Cooksley,Geert Leroux-Roels,F Von Sonnenburg +11 more
TL;DR: There is no evidence to lend support to HAV booster vaccination after a full primary vaccination course in a healthy individual, and further investigations are needed before deciding if boosters can be omitted in special patient-groups.
Journal ArticleDOI
A pilot study of therapeutic vaccination with envelope protein E1 in 35 patients with chronic hepatitis C.
Frederik Nevens,Tania Roskams,Hans Van Vlierberghe,Yves Horsmans,Dirk Sprengers,A. Elewaut,Valeer Desmet,Geert Leroux-Roels,Emmanuel Quinaux,Erik Depla,Stéphanie Dincq,Christine Vander Stichele,Geert Maertens,Frank Hulstaert +13 more
TL;DR: The increase in anti‐E1 antibody levels correlated with the decrease in total Ishak score and with the relative decreases in both Ishak fibrosis score and ALT level and the observed effects warrant further study.
Journal ArticleDOI
AS03-adjuvanted versus non-adjuvanted inactivated trivalent influenza vaccine against seasonal influenza in elderly people: a phase 3 randomised trial
Janet E. McElhaney,Jiri Beran,Jeanne-Marie Devaster,Meral Esen,Odile Launay,Geert Leroux-Roels,Guillermo M. Ruiz-Palacios,Gerrit A van Essen,Adrian Caplanusi,Carine Claeys,Christelle Durand,Xavier Duval,Mohamed El Idrissi,Ann R. Falsey,Gregory Feldman,Sharon E. Frey,Florence Galtier,Shinn-Jang Hwang,Shinn-Jang Hwang,Bruce L. Innis,Martina Kovac,Peter G. Kremsner,Shelly A. McNeil,Andrzej Nowakowski,Jan Hendrik Richardus,Andrew F. Trofa,Lidia Oostvogels +26 more
TL;DR: AS03-adjuvanted inactivated trivalent influenza vaccine (TIV) has a higher efficacy for prevention of some subtypes of influenza than does a non-adJuvanted TIV, and future influenza vaccine studies in elderly people should be based on subtype or lineage-specific endpoints.
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Improved CD4+ T cell responses to Mycobacterium tuberculosis in PPD-negative adults by M72/AS01 as compared to the M72/AS02 and Mtb72F/AS02 tuberculosis candidate vaccine formulations: A randomized trial
Isabel Leroux-Roels,Sheron Forgus,Fien De Boever,Frédéric Clement,Marie-Ange Demoitié,Pascal Mettens,Philippe Moris,Edouard Ledent,Geert Leroux-Roels,Opokua Ofori-Anyinam +9 more
TL;DR: This first clinical study with M72/AS01 and M72-naïve adults of vaccines containing M72 antigen showed that both vaccines were clinically well tolerated and induced high magnitude and persistent cell-mediated and humoral immune responses.
Journal ArticleDOI
The first combined vaccine against hepatitis A and B: an overview.
S. Thoelen,P. Van Damme,A Leentvaar-Kuypers,Geert Leroux-Roels,M Bruguera,P. C. Frei,V Bakasenas,Assad Safary +7 more
TL;DR: The combined hepatitis A and B vaccine Twinrix proves to be consistently safe, well tolerated and highly immunogenic and compares well with serological responses reached with monovalent vaccines.