M
M. Angela Nieto
Researcher at Spanish National Research Council
Publications - 106
Citations - 30976
M. Angela Nieto is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Snail & Epithelial–mesenchymal transition. The author has an hindex of 53, co-authored 102 publications receiving 27559 citations. Previous affiliations of M. Angela Nieto include Universidad Miguel Hernández de Elche.
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Journal ArticleDOI
Epithelial-Mesenchymal Transitions in Development and Disease
Jean Paul Thiery,Jean Paul Thiery,Hervé Acloque,Ruby Yun-Ju Huang,Ruby Yun-Ju Huang,M. Angela Nieto +5 more
TL;DR: The mesenchymal state is associated with the capacity of cells to migrate to distant organs and maintain stemness, allowing their subsequent differentiation into multiple cell types during development and the initiation of metastasis.
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The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression
Amparo Cano,Mirna Perez-Moreno,Isabel Rodrigo,Annamaria Locascio,Maria Blanco,Marta G. del Barrio,Francisco Portillo,M. Angela Nieto +7 more
TL;DR: It is shown that mouse Snail is a strong repressor of transcription of the E-cadherin gene, opening up new avenues for the design of specific anti-invasive drugs.
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The snail superfamily of zinc-finger transcription factors.
TL;DR: The Snail superfamily of zinc-finger transcription factors is involved in processes that imply pronounced cell movements, both during embryonic development and in the acquisition of invasive and migratory properties during tumour progression.
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The Snail genes as inducers of cell movement and survival: implications in development and cancer
TL;DR: It is proposed that Snail genes act primarily as survival factors and inducers of cell movement, rather than as inducersof EMT or cell fate.
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EMT in cancer
TL;DR: Four scientists have been asked for their opinions on the role of EMT in cancer and the challenges faced by scientists working in this fast-moving field.