G
Geoffrey Camirand
Researcher at University of Pittsburgh
Publications - 23
Citations - 1229
Geoffrey Camirand is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Transplantation & CD8. The author has an hindex of 15, co-authored 21 publications receiving 1098 citations. Previous affiliations of Geoffrey Camirand include Laval University.
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Journal ArticleDOI
Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice
Qing Ding,Melissa Y. Yeung,Geoffrey Camirand,Qiang Zeng,Hisaya Akiba,Hideo Yagita,Geetha Chalasani,Mohamed H. Sayegh,Nader Najafian,David M. Rothstein +9 more
TL;DR: The findings suggest that TIM-1 may be a novel therapeutic target for modulating the immune response and provide insight into the signals involved in the generation and induction of Bregs.
Journal ArticleDOI
Intracellular delivery of a Tat-eGFP fusion protein into muscle cells.
Nicolas Caron,Yvan Torrente,Yvan Torrente,Geoffrey Camirand,Mathieu Bujold,Pierre Chapdelaine,Karine Leriche,Nereo Bresolin,Jacques P. Tremblay +8 more
TL;DR: Muscles injected with Tat-eGFP showed intense labeling of the extracellular matrix (ECM), suggesting that, although Tat fusion proteins can transduce muscle fibers, their binding by components of the ECM surrounding myofibers could interfere with the intracellular transduction process.
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Cognate antigen directs CD8+ T cell migration to vascularized transplants
Jeffrey M. Walch,Qiang Zeng,Qi Li,Martin H. Oberbarnscheidt,Rosemary A. Hoffman,Amanda L. Williams,David M. Rothstein,Warren D. Shlomchik,Jiyun V. Kim,Geoffrey Camirand,Fadi G. Lakkis +10 more
TL;DR: It is demonstrated in vivo that cognate antigen was necessary for the firm adhesion and transendothelial migration of CD8+ effector T cells specific to graft antigens and that both steps occurred independent of Gαi signaling.
Journal ArticleDOI
Identification of a putative pathway for the muscle homing of stem cells in a muscular dystrophy model
Yvan Torrente,Geoffrey Camirand,Federica Pisati,Marzia Belicchi,Barbara Rossi,Fabio Colombo,Mosthapha El Fahime,Nicolas Caron,Andrew C. Issekutz,Gabriela Constantin,Jacques P. Tremblay,Nereo Bresolin +11 more
TL;DR: It is shown for the first time that the expression of the adhesion molecule L-selectin is important for muscle homing of MDSCs, and this discovery will aid in the improvement of a potential therapy for muscular dystrophy based on the systemic delivery of M DSCs.
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Graft‐infiltrating PD‐L1hi cross‐dressed dendritic cells regulate antidonor T cell responses in mouse liver transplant tolerance
Yoshihiro Ono,Angelica Perez-Gutierrez,Toshimasa Nakao,Helong Dai,Geoffrey Camirand,Osamu Yoshida,Shinichiro Yokota,Donna B. Stolz,Mark A. Ross,Adrian E. Morelli,David A. Geller,Angus W. Thomson +11 more
TL;DR: Findings suggest that graft‐infiltrating PD‐L1hi CD‐DCs may play a key role in the regulation of alloimmunity and in the induction of liver transplant tolerance.