G
Geoffrey N. Smith
Researcher at University of British Columbia
Publications - 64
Citations - 2126
Geoffrey N. Smith is an academic researcher from University of British Columbia. The author has contributed to research in topics: Psychosis & Schizophrenia. The author has an hindex of 25, co-authored 64 publications receiving 1962 citations. Previous affiliations of Geoffrey N. Smith include Riverview Hospital & St. Vincent's Health System.
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Journal ArticleDOI
Abnormalities of myelination in schizophrenia detected in vivo with MRI, and post-mortem with analysis of oligodendrocyte proteins
Sean W. Flynn,Donna J. Lang,Alex L. MacKay,Vina M. Goghari,Irene M. Vavasour,Kenneth P. Whittall,Geoffrey N. Smith,Victoria Arango,Victoria Arango,J. John Mann,J. John Mann,Andrew J. Dwork,Andrew J. Dwork,Peter Falkai,William G. Honer +14 more
TL;DR: In healthy subjects, myelin water fraction in total white matter and in frontal white matter increased with age, and with years of education, indicating ongoing maturation, and in patients with schizophrenia, neither relation was statistically significant.
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An MRI study of basal ganglia volumes in first-episode schizophrenia patients treated with risperidone.
Donna J. Lang,Lili C. Kopala,Robert Vandorpe,Qing Rui,Geoffrey N. Smith,Vina M. Goghari,William G. Honer +6 more
TL;DR: This group of first-episode patients did not exhibit abnormalities of basalganglia volumes, nor were basal ganglia volumes affected by exposure to risperidone, suggesting effects of both illness and medications.
Journal ArticleDOI
Ventricular and sulcal size at the onset of psychosis.
William G. Iacono,Geoffrey N. Smith,Margaret Moreau,Morton Beiser,Jonathan A.E. Fleming,Tsung-yi Lin,Borys Flak +6 more
TL;DR: To determine whether abnormalities in brain morphology are present at the onset of illness, patients with schizophrenia, schizophreniform and bipolar disorders, and major depression who were experiencing their first episodes of psychosis were compared with normal and medical control subjects.
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The hotel study: multimorbidity in a community sample living in marginal housing.
Fidel Vila-Rodriguez,William J. Panenka,Donna J. Lang,Allen E. Thornton,Talia Vertinsky,Hubert Wong,Alasdair M. Barr,Ric M. Procyshyn,J.J. Sidhu,Geoffrey N. Smith,Tari Buchanan,Mel Krajden,Michael Krausz,Julio S. G. Montaner,G. William MacEwan,William G. Honer +15 more
TL;DR: This marginally housed cohort had greater than expected mortality and high levels of multimorbidity with adverse associations with role function and likelihood of treatment for psychosis, which may guide the development of effective health care delivery in the setting of marginal housing.
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Reduced Basal Ganglia Volumes After Switching to Olanzapine in Chronically Treated Patients With Schizophrenia
Donna J. Lang,Lili C. Kopala,Robert Vandorpe,Qing Rui,Geoffrey N. Smith,Vina M. Goghari,J S Lapointe,William G. Honer +7 more
TL;DR: Olanzapine reversed putamen and globus pallidus enlargement induced by typical antipsychotics but did not alter volumes in patients previously treated with risperidone.