Gerd Birkenmeier

TL;DR: This work demonstrates a heretofore unrecognized collaborative interaction between MCs and DCs leading to the elicitation of specific immune responses, including 60- and 70-kDa heat shock proteins.

TL;DR: Results indicate that inhibition of Glo1 by curcumin may result in non-tolerable levels of MGO and GSH, which, in turn, modulate various metabolic cellular pathways including depletion of cellular ATP and G SH content.

TL;DR: The current knowledge on T(H)17 in autoimmunity is summarized with emphasis on its differentiation factors and some mechanisms involved in initiating pathological events of autoIMmunity.

TL;DR: It is shown for the first time that Glo1 activity directly can be regulated by an oxidative posttranslational modification that was found in the native enzyme, i.e, glutathionylation, which is expected to be important factors within the context of redox-dependent regulation of glucose metabolism in cells.

TL;DR: The occurrence of apoE and immunoglobulin G in SVD lesions and in the perivascular space suggests that the presence of SVD results in plasma-protein leakage into the brain.