G
Gerhard Dobler
Researcher at Bundeswehr Institute of Microbiology
Publications - 34
Citations - 1033
Gerhard Dobler is an academic researcher from Bundeswehr Institute of Microbiology. The author has contributed to research in topics: Tick & Tick-borne encephalitis virus. The author has an hindex of 15, co-authored 34 publications receiving 855 citations.
Papers
More filters
Journal ArticleDOI
Emergence of zoonotic arboviruses by animal trade and migration
Martin Pfeffer,Gerhard Dobler +1 more
TL;DR: The known ecology of the mosquito-borne equine encephalitis viruses, as well as Tick-Borne Encephalitis virus and its North American counterpart Powassan virus are outlined, and the most likely mode that these viruses could expand their respective geographical range is discussed.
Journal ArticleDOI
Viperin is an iron-sulfur protein that inhibits genome synthesis of tick-borne encephalitis virus via radical SAM domain activity
Arunkumar S. Upadhyay,Kirstin Vonderstein,Andreas Pichlmair,Oliver Stehling,Keiryn L. Bennett,Gerhard Dobler,Ju-Tao Guo,Giulio Superti-Furga,Roland Lill,Roland Lill,Anna K. Överby,Anna K. Överby,Friedemann Weber,Friedemann Weber +13 more
TL;DR: The data suggest that viperin requires CIAO1 for [4Fe‐4S] cluster assembly, and acts through an enzymatic, Fe‐S cluster‐ and SAM‐dependent mechanism to inhibit viral RNA synthesis.
Journal ArticleDOI
A new Puumala hantavirus subtype in rodents associated with an outbreak of Nephropathia epidemica in South-East Germany in 2004.
Sandra Essbauer,J. Schmidt,Franz Josef Conraths,Robert Friedrich,Judith Koch,W. Hautmann,M. Pfeffer,Roman Wölfel,J. Finke,Gerhard Dobler,Rainer G. Ulrich +10 more
TL;DR: Serological and genetic investigations revealed that Puumala virus (PUUV) is dominant in the local population of bank voles and seems to be responsible for the observed increase of human hantavirus infections in 2004–2005.
Journal ArticleDOI
Tick-borne encephalitis virus in dogs - is this an issue?
Martin Pfeffer,Gerhard Dobler +1 more
TL;DR: The last review on Tick-borne encephalitis (TBE) in dogs was published almost ten years ago and this zoonotic tick-borne arbovirus has been geographically spreading and emerging in many regions in Eurasia and continues to do so.
Journal ArticleDOI
Virus detection in questing ticks is not a sensitive indicator for risk assessment of tick-borne encephalitis in humans.
Paweł Stefanoff,Martin Pfeffer,Wiebke Hellenbrand,J. Rogalska,F. Rühe,Agata Makowka,Jerzy Michalik,B. Wodecka,A. Rymaszewska,D. Kiewra,A. Baumann-Popczyk,Gerhard Dobler +11 more
TL;DR: It is concluded that the collection and screening of ticks by real‐time RT‐PCR cannot be recommended for assessment of human TBE risk, and alternative methods of environmental TBEV monitoring should be considered, such as serological monitoring of rodents or other wildlife.