G
Germano Cecere
Researcher at Pasteur Institute
Publications - 27
Citations - 537
Germano Cecere is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Argonaute & RNA interference. The author has an hindex of 10, co-authored 26 publications receiving 387 citations. Previous affiliations of Germano Cecere include Columbia University & Sapienza University of Rome.
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Journal ArticleDOI
Promoters Recognized by Forkhead Proteins Exist for Individual 21U-RNAs
TL;DR: This work establishes that the most conserved 8-mer sequence in the upstream region of 21U-RNAs, CTGTTTCA, is absolutely required for their individual expression and suggests that thousands of small noncoding transcription units are regulated by FKH proteins.
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Global effects of the CSR-1 RNA interference pathway on the transcriptional landscape.
TL;DR: It is proposed that the CSR-1 pathway helps maintain the directionality of active transcription, thereby propagating the distinction between transcriptionally active and silent genomic regions.
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Small-RNA-mediated transgenerational silencing of histone genes impairs fertility in piRNA mutants.
Giorgia Barucci,Giorgia Barucci,Eric Cornes,Meetali Singh,Blaise Li,Martino Ugolini,Aleksei Samolygo,Aleksei Samolygo,Céline Didier,Florent Dingli,Damarys Loew,Piergiuseppe Quarato,Piergiuseppe Quarato,Germano Cecere +13 more
TL;DR: It is concluded that sRNA-mediated silencing of histone genes impairs the fertility of piRNA mutants and may serve to maintain piRNAs across evolution.
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The ZFP-1(AF10)/DOT-1 Complex Opposes H2B Ubiquitination to Reduce Pol II Transcription
TL;DR: ZFP-1 and its interacting partner DOT-1.1 have a global role in negatively modulating the level of polymerase II (Pol II) transcription on essential widely expressed genes and contribute to progressive Pol II pausing on essential genes during development and to rapid Pol IIPausing during stress response.
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The RNA-dependent RNA polymerase essential for post-transcriptional gene silencing in Neurospora crassa interacts with replication protein A
Tony Nolan,Germano Cecere,Carmine Mancone,Tonino Alonzi,Marco Tripodi,Caterina Catalanotto,Carlo Cogoni +6 more
TL;DR: Supporting a link between the two proteins, it is found that the accumulation of short interfering RNAs (siRNAs), the hallmark of silencing, is dependent on an ongoing DNA synthesis.